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Nuclear factor I
Nuclear
factor
I
is a
family
of closely related
transcription factors
. They constitutively
bind
as
dimers
to
specific
sequences
of
DNA
with high
affinity
.
Family members
contain
an
unusual
DNA binding domain
that
binds
to the
recognition sequence
5'-TTGGCXXXXXGCCAA-3'.
Subtypes
include:
NFIA
NFIB
NFIC
NFIX