The school was the 141st-ranked public high school in New Jersey out of 339 schools statewide in New Jersey Monthly magazine's September 2014 cover story on the state's "Top Public High Schools", using a new ranking methodology. The school had been ranked 156th in the state of 328 schools in 2012, after being ranked 186th in 2010 out of 322 schools listed. The magazine ranked the school 153rd in 2008 out of 316 schools. The school was ranked 184th in the magazine's September 2006 issue, which surveyed 316 schools across the state. Schooldigger.com ranked the school 119th out of 381 public high schools statewide in its 2011 rankings which were based on the combined percentage of students classified as proficient or above proficient on the mathematics and language arts literacy components of the High School Proficiency Assessment.
Athletics
The Northern Burlington County Regional High School Greyhounds compete in the Liberty Division of the Burlington County Scholastic League, which operates under the jurisdiction of the New Jersey State Interscholastic Athletic Association and consists of public and non-public high schools covering Burlington County, Mercer County and Ocean County in Central Jersey. With 1,020 students in grades 10-12, the school was classified by the NJSIAA for the 2015-16 school year as Central Jersey, Group III for most athletic competition purposes, which included schools with an enrollment of 822 to 1,068 students in that grade range. The school had previously competed in Group II, but the growth in the district's population has resulted in moving up to Group III. The football team competes in the Patriot Division of the 95-team West Jersey Football League superconference and was classified by the NJSIAA as Central Jersey Group IV for football for 2017-18. The school's mascot is the Greyhound, and colors are blue and grey. In 2013, Northern Burlington's Board of Education officially branded and approved the school "NB" logo and school fight song. ;Sectional and district championships
Baseball - 2015 Central Jersey Group III semifinals
Baseball - 2013 Central Jersey Group III
Boys' basketball - 1972-73 South Jersey Group III
Boys' bowling - 1996-97 South Jersey Group II
Boys' soccer - 2001 South Jersey Group II
Boys' track - 2012 Central Jersey Group III
Field hockey - 1999 Central Jersey Group II
Girls' basketball - 2003 South Jersey Group II
Girls' volleyball - 2010 South Jersey Group II
Golf - 2016 state champions
Softball - 1980, 1982, 1992, 2002, 2005 South Jersey Group II
Wrestling - 2000-01, 2004–05, 2005-06 2010-11, 2012–13, 2014-2015 District 25 champions
Football - 1971 Undefeated Delaware Valley League Champions
Football - 1972 Undefeated Delaware Valley League Champions
;State championships / football state sectional titles
Football - 1980 undefeated South Jersey Group II state champions and 1995 South Jersey Group II state champions
Girls' basketball - 2003 Group II state championship vs. Newton High School. 2003 South Jersey Group II vs. Haddonfield Memorial High School.
Softball - 2002 Group II state championship vs. Pompton Lakes High School
Extracurricular Activities
At Northern there are many different activities for students to partake in there are about 50 clubs some of these clubs include Interact, a community ethics club, where students join forces to help the community, such as Ten Thousand Villages Sale, Relay for Life, Care Bags for Kids, nursing home party. Another example being Video Club where students talk and help produce Northern TV, Northern's own television station which provides news to its sending districts.
Special Education Program
The Special Education Program at Northern Burlington Regional High School focuses on the promotion of tolerance and appreciation of diversity of all variations. The Northern Burlington Regional High School provides Special Education students with a multitude of programs, such as in-class support, a variety of resource classrooms, replacement classes customized to the individual's particular needs as well as a Multiple Disabilities/Autistic program. The Northern Burlington Regional High School has established a Special Services Department, including Speech, Language and Behavioral Therapists, Instructional Assists as well as Special Education teachers at both the middle and high school levels.
Administration
The school's principal is Dr. Sally Lopez. Her core administration team includes three assistant principals.