The NV uses the same F-Alphaplatform as does the Nissan Titanfull-size pickup, but due to the need for a flat loading floor it is highly modified and they end up sharing mainly powertrain pieces and some appearance aspects. The NV is also only available with rear-wheel drive, coupled to a five-speed automatic transmission. The NV is not targeted directly at the buyers of the Ford E-Series and Chevrolet Express, but rather at private buyers including contractors and small business owners that are looking for a vehicle that is both capable and comfortable. The 4.0-litre V6 engine outputs 261 hp and 281 lb-ft of torque, while the 5.6-litre V8 engine outputs 317 hp and 385 lb-ft of torque. The V8-engined versions are also electronically limited to a top speed of.
NV1500
The NV1500 has a load capacity of, similar to the GMC/Chevrolet cargo van using the same "1500" designation, and informally known as a "half-ton". It is only available with the 4-litre V6. It is available in S or SV trim, with the SV receiving power door locks, windows, outside mirrors and 17" styled steel wheels.
NV2500
The NV2500 HD is equipped with the 4-litre V6 engine, with the bigger V8 available as an option. The payload is, similar to the GMC/Chevrolet cargo van using the same "2500" designation, and informally known as a "three-quarter-ton". It comes in S, SV, or SL trim levels and is available in low or high roof; the SL is only available with the V6. The SV trim features a lockable center console with power outlets as well as an additional 120 V outlet in the cargo compartment along with features from the 1500 SV while the SL trim adds chrome bumpers, grille, and door handles and 17" chrome wheels.
NV3500
The NV3500 HD is the heaviest weight class offered, and is only available with the large 5.6-litre V8 engine with either a low or a high roof. Payload capacity is, similar to the GMC/Chevrolet cargo van using the same "3500" designation, and informally known as a "one-ton". The NV3500 has a rollover risk of 30.6%. It is also the only weight class offered in passenger van configuration. Unusually, the latter is offered with a V6 or a V8, unlike its V8-only cargo counterpart. The NV3500 comes in S, SV or SL trim levels.