The university is located at a distance of 3 km from the city centre. The campus is spread over of land. Nishtar Hospital, one of the largest hospitals in Pakistan, is located adjacent to the college. The total area of the campus, hospital and hostel area is more than. The city of Multan is one of the hottest localities of Pakistan; this is reflected in architecture of the college and hospital – high ceilings and large windows are commonplace. The college itself is spacious, with the various academic departments housed around a central quadrangle. The quadrangle is a large garden used for student functions and gatherings. There is an attached hospital, adjacent hostels, and faculty residential colony. The college as well as the hostels are nostalgic of old Islamic architecture. The buildings added to the campus in the 1960s to early 1980s were designed by A. R. Hye.
Admissions
;Medical & Dental College: Admission to all public medical & dental colleges is through a centralized system at the provincial level. Students are eligible to apply for MBBS or BDS programs after Higher Secondary School Certificate or equivalent examination. Candidates are selected by a rigorous admission process that includes a competitive centralized Medical & Dental College Admission Test conducted by University of Health Sciences Lahore annually. Merit is determined by the marks obtained on the MDCAT & Higher Secondary School Certificate or equivalent examination. Foreign/International students can apply for admission through the Higher Education Commission of Pakistan. ;College of Nursing: Students can apply for 4 year BSN program after HSSC or equivalent examination. There is no central admission policy for nursing colleges. Students apply directly to college of nursing for admission consideration. Students accepted to BSN program are offered monthly stipend equivalent to BS-17.
Student life
Students come from province of Punjab and other parts of Pakistan, as well as from several other countries, including Jordan, Palestine, Nepal, Sri Lanka, Bangladesh and other African and Middle Eastern countries. Most choose to live in the hostels on the campus.
Nishtar Medical University has the following departments: ;Basic Health Sciences departments ;Clinical Health Sciences departments In addition, allied specialty exposure is ensured in different subspecialties of medicine and surgery. ;Teaching hospitals
Alumni
Nishtar Medical College graduates have a strong alumni presence in United States. Nishtar Alumni Association of North America continues to fund one major project every year. Some of the continuing and past projects include 25 scholarships per year, extension project of the paediatrics ward, conference room in the ER, GI/Endoscopy suite, establishment of cardiac catheterization lab, IT and Simulation Lab for the students.
Founding Father
Dr. Jamal Bhutta was the founding principal and medical superintendent of the institute.