After being educated at playing school football at Waverley College in Sydney, Rizzo arrived in England in 1996 joining English giants Liverpool. Although not capped in the first team, the then 18 year old was an unused substitute on six occasions in the Premier League season 1997/98. He was then lured to Crystal Palace by Terry Venables for two seasons and featured in 35 league games before moving to Italian Serie B side Ternana in 2000. At Palace he scored three times; once in the league against Norwich City and twice in a League Cup tie against Colchester United. Following three injury plagued seasons with a knee injury in Italy he then joined English League 1 side Milton Keynes Dons on a free transfer in November 2004, where he became a firm favourite with the fans. He is a lively and tricky player, known for his crossing and readiness to shoot on sight as well as his hard work and discipline. The summer of 2006 was not the best of times for Rizzo, who featured in the Dons' first pre-season game against Derby County but suffered with injury later in the season before going on loan to league two side Grimsby Town and then league one side Chesterfield in 2007. It was announced on 8 May 2007 that Rizzo's contract with M K Dons had been terminated by mutual consent. He then signed a two-year contract with Perth Glory on 19 May 2007, and made his debut on 26 August 2007, coming on in the 69th minute for Naum Sekulovski in a game against the Newcastle Jets. Rizzo was not offered a new contract at Perth Glory, and went on to sign a short-term deal for the Central Coast Mariners to play in their AFC Champions League campaign. It was announced on 20 May 2009, that Nick Rizzo's contract with Central Coast Mariners would not be re-signed. Rizzo went on to play for APIA Leichhardt Tigers until 2011.
International career
Nicky has represented Australia at the U17, U20, U23 level and is a full Australian international when he played for the Socceroos against Croatia in 1998. He also played in the 2000 Olympics for the Australian U23 team which failed to go past the group stages.
Coaching career
Since retiring Rizzo has set up his own soccer school named "Nick Rizzo International Football School".