Nicholas Wald


Sir Nicholas John Wald FRS, FRCP, FMedSci, qualified in medicine from University College London in 1967. He is currently Honorary Professor of Preventive Medicine, University College London, Honorary Professor, Population Health Research Institute, St George's University of London, Visiting Professor, University of Oxford, and Honorary Consultant and Adjunct Professor, Brown University RI USA. He was Professor of Environmental and Preventive Medicine from 1983 to 2019 at St Bartholomew's Hospital Medical College. He was co-founder and director of the Wolfson Institute of Preventive Medicine.
In the 1970s, he showed that fetal neural tube defects could be detected by measuring alpha-fetoprotein in the pregnant woman’s blood. He was the innovator of the “MoM”, or multiple of the median, a measure of the level of screening markers. He, with colleagues, first described the Triple test, Combined test, Quad test, Integrated test and Reflex DNA test.
In 1986 Wald showed that environmental tobacco smoke was a cause of lung cancer and was a member of the US National Academy of Sciences Committee - the first public body that reached this conclusion. In 2003 with Professor Law, he showed that environmental tobacco smoke also caused cardiovascular disease.
In 1991 Professor Wald showed that folic acid supplementation prevented most cases of neural tube defects.
In 1999, together with Malcolm Law, he invented the polypill.
He received in 2000, the Joseph P. Kennedy Jr. Foundation Award., was elected a Fellow of the Royal Society in 2004, and knighted in the 2008 Birthday Honours for services to preventive medicine. In 2019 he was elected member of the US National Academy of Medicine.