Niccolò

• Niccolò Ammaniti, Italian writer
• Niccolò Machiavelli, political philosopher, musician, poet, and romantic comedic playwright
• Niccolò Massa, Italian anatomist who wrote an early anatomy text Anatomiae Libri Introductorius in 1536

• Niccolò Antonio Zingarelli, composer
• Niccolò Castiglioni, Italian composer and pianist
• Niccolò da Perugia, Italian composer of the trecento
• Niccolò Jommelli, Italian composer
• Niccolò Paganini, Italian violinist, violist, guitarist and composer
• Niccolò Piccinni, Italian composer of classical music and opera

• Niccolò dell'Abbate, Italian Mannerist painter and decorator
• Niccolò Tribolo, Florentine Mannerist artist in the service of Cosimo I de' Medici

• Niccolò Alamanni, Roman antiquary of Greek origin
• Niccolò Cacciatore, Italian astronomer
• Niccolò Da Conti, Venetian merchant and explorer
• Niccolò Polo, Venetian merchant and explorer, father of Marco Polo.
• Niccolò de' Niccoli, Italian Renaissance humanist
• Niccolò Fontana Tartaglia, mathematician
• Niccolò Piccinino, Italian condottiero
• Niccolò II and Niccolò III d'Este, rulers of Ferrara
• Nicholas de Fleury, central character in The House of Niccolò series of books by Dorothy Dunnett
• Niccolò Canepa, Genovese motorcycle racer, competing in MotoGP with Ducati, 2007 Superstock 1000 F.I.M. Cup world champion