NME2


Nucleoside diphosphate kinase B is an enzyme that in humans is encoded by the NME2 gene.

Function

Nucleoside diphosphate kinase exists as a hexamer composed of 'A' and 'B' isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene generates naturally occurring transcripts which encode a fusion protein consisting of sequence sharing identity with each individual gene product.

Interactions

NME2 has been shown to interact with NME3 and HERC5.