Musa'id married Watfa, a daughter of Muhammad bin Talal, the 12thRashidi amir. Their son Faisal bin Musaid was born in Riyadh on 4 April 1944. He subsequently divorced Watfa. His sons and daughters by Watfa were much closer to their maternal Rashidi relatives than their paternal relatives, Al Sauds. In 1965, his son Khaled, who was a fervent Wahhabite, was killed during a Riyadh protest against the introduction of television in Saudi Arabia. The details of his death are disputed. Some reports allege that he died resisting arrest outside his own home. No investigation over his death was ever initiated. Musa'id had another son, Bandar, and a daughter, Al Jawhara. He also had another son Abdul Rahman bin Musaid from a subsequent marriage. Abdullah bin Musa'id, another son, is a businessman and the owner of Sheffield United.
Assassination of King Faisal
On 25 March 1975 his son Faisal bin Musaid went to the Royal Palace in Riyadh, where King Faisal was holding a majlis. He joined a Kuwaiti delegation and lined up to meet the king. The king recognized his nephew and bent his head forward, so that the younger Faisal could kiss the king's head in a sign of respect. The prince took out a revolver from his robe and shot the King twice in the head. His third shot missed and he threw the gun away. King Faisal fell to the floor. Bodyguards with swords and submachine guns arrested the prince. The king was quickly rushed to a hospital but doctors failed to save him. Initial reports described Faisal bin Musaid as "mentally deranged." He was moved to a Riyadh prison. He was deemed sane to be tried. He was found guilty of murder. Hours after the verdict, he was publicly decapitated in Riyadh. The assassin's brother Bandar was also imprisoned, but was released a year later.
Later life
Prince Musa'id did not hold any significant administrative positions and hence he was sidelined for the throne. The involvement of his son Faisal in the assassination of King Faisal could also have weakened his position. In addition he seemingly never sought one. He gradually lost his eyesight after the death of his first son, Khalid. He lived an austere private life where he was known to be pious.
Death
The Royal Diwan announced that Prince Musa'id had died on 19 August 2013. He was the second eldest living son of Ibn Saud at the time of his death next only to Prince Bandar bin Abdulaziz Al Saud. It was announced that funeral prayers for the late prince would be held at Imam Turki bin Abdullah Mosque in Riyadh the next day and a three-day mourning period was also declared.