As a senior architect, he started to work at the newly opened Yerevan Project Institute, in Gevorg Tamanyan studio. He designed several projects: residential and administrative buildings, schools, designed the plans of the settlement after Lukashin and the settlements of Kanaker Hydro Power Plant Since 1964, he worked at Academy of Arts of the Academy of Sciences of the Republic of Armenia as a junior researcher, then he became the Scientific Secretary of the Institute. In 1969 he became a Candidate of Sciences with defending his thesis on "“Architectural complexes of Syunik region 16-18th centuries". He has headed the Architecture Department of the Institute of Arts of the Armenian Academy of Sciences since 1988. Since 1999 he teaches at the Yerevan State university.
Researches
M. Hasratyan has measured around 150 monuments in Armenia. He was the first one to research and put into scientific circulation: Tashi’s monument, early medieval monuments of Ddmashen, Sarakap, the monasteries in Artsakh- Amaras, Dadivank, Khratravank, Gandzasar Monastery, Gtchavank, and numerous churches, including the famous Ghazanchetsots Cathedral, have been measured by the medieval Armenian architectural monuments of the Nagorno-Karabakh region. In Nakhichevan Hasratyan "has been measuring, analyzing, and putting in scientific circulation many monuments, including the Astrapid Red Monastery, which had been destroyed by the “owners” of Nakhichevan not long after and continues to exist only in M. Hasratyan's assessments and descriptions. He was the first to explore the Armenian-Byzantine, Armenian-Georgian, Armenian-Iranian architectural relations
Books
Hasratyan is the author of nearly two dozen books, numerous brochures, hundreds of articles, theses, reviews and encyclopedia articles published in Armenia, Moscow, Kiev, Tbilisi, Paris, Lyon, Vienna, Lisbon, Rome, Venice, Milan, Bologna, Naples, Montreal, Yokohama, Ankara. Hasratyan's first book was about the architecture of Yerevan, his birthplace, which was published in Moscow on the 2750th anniversary of the founding of Yerevan in 1968, in co-authorship with Varazdat Harutyunyan and Arsen Melikyan in 1968. The same composition of the author on the occasion of the 50th anniversary of the USSR was published in Moscow in 1972 by the "Architecture of Soviet Armenia"։ For the collective fundamental work of "History of Armenian Art", which authored sections dedicated to the history of Armenian architecture Hasratyan was awarded the 2009 State Prize in Fine Arts. Co-author of several Armenian architectural history..