Moritz Kaposi


Moritz Kaposi was a Hungarian physician and dermatologist who discovered the skin tumor that received his name.

Biography

Early life and name

Born to a Jewish family, originally his surname was Kohn; but, with his conversion to the Catholic faith, he changed it to Kaposi in 1871, in reference to his town of birth. One purported reason behind this is that he wanted to marry a daughter of current dermatology chairman, Ferdinand Ritter von Hebra, and advance in the society, which he could not have done being of Jewish faith. This seems unlikely because he married Martha Hebra and converted to Catholicism several years prior to changing his name, by which time he was already well established in the Vienna University faculty and a close associate of her father, Ferdinand. A more plausible explanation is based on his own comments to colleagues that he changed his name to avoid confusion with five other similarly named physicians on the Vienna faculty. Rumors about the sincerity of both his marriage and his concerns about his Jewish ancestry may have arisen through professional jealousy

Education and career

In 1855, Kaposi began to study medicine at the University of Vienna and attained a doctorate in 1861. In his dissertation, titled Dermatologie und Syphilis he made an important contribution to the field. Kaposi was appointed as professor at the University of Vienna in 1875, and in 1881 he became a member of the board of the Vienna General Hospital and director of its clinic of skin diseases.
Together with his mentor, Ferdinand Ritter von Hebra, he authored the book Lehrbuch der Hautkrankheiten in 1878. Kaposi’s main work, however, was Pathologie und Therapie der Hautkrankheiten in Vorlesungen für praktische Ärzte und Studierende, published in 1880, which became one of the most significant books in the history of dermatology, being translated to several languages. He is credited with the description of xeroderma pigmentosum, a rare genetic disorder now known to be caused by defects in nucleotide excision repair. Among other diseases, Kaposi was the first to study Lichen scrofolosorum and Lupus erythematosus. In all, he published over 150 books and papers. He is widely credited with advancing the use of pathologic examination in the diagnosis of dermatologic diseases.

Kaposi's sarcoma

His name entered into the history of medicine in 1872, when he described for the first time Kaposi's sarcoma, a cancer of the skin, which he had discovered in five elderly male patients and which he initially named "idiopathic multiple pigmented sarcoma". More than a century later, the appearance of this disease in young gay men in New York City, San Francisco and other coastal cities in the United States was one of the first indications that a new disease, now called AIDS, had appeared. Kaposi's sarcoma is a tumor that is caused by a virus, Kaposi's sarcoma-associated herpesvirus or KSHV, discovered in 1993. Kaposi's sarcoma is now the most commonly reported cancer in parts of sub-Saharan Africa.
According to his biographer, Dr. J.D. Oriel, "in his lifetime, Moritz Kaposi was acknowledged as one of the great masters of the Vienna School of Dermatology, a superb clinician and renowned teacher". While his mentor, Ferdinand von Hebra, is considered the "father of dermatology", Kaposi was one of the first to establish dermatology on its anatomical pathology scientific basis. He became the chairman of the Vienna School of Dermatology, after Hebra's death in 1880.

Works