Monongahela virus


Monongahela virus is a single-stranded, negative-sense Orthohantavirus virus of zoonotic origin that causes Hantavirus pulmonary syndrome.

Discovery of virus

Monongahela virus was first detected in Peromyscus maniculatus nubiterrae captured in the Monongahela National Forest in West Virginia in 1985.

Transmission

This member virus of Sin Nombre orthohantavirus has not been shown to transfer from person to person. Transmission by aerosolized rodent excreta still remains the only known way the virus is transmitted to humans. In general, droplet and/or fomite transfer has not been shown in the hantaviruses in either the hemorrhagic or pulmonary forms.
In two cases in Pennsylvania, the patients were living in rural areas and had recent exposure to rodent excreta prior to the onset of symptoms. Both patients developed rapid onset of respiratory distress and pulmonary edema, believed to be the result of cytokine storm, and both expired within 5 days of onset of symptoms.