Monitoring (medicine)


In medicine, monitoring is the observation of a disease, condition or one or several medical parameters over time.
It can be performed by continuously measuring certain parameters by using a medical monitor, and/or by repeatedly performing medical tests.
Transmitting data from a monitor to a distant monitoring station is known as telemetry or biotelemetry.

Classification by target parameter

Monitoring can be classified by the target of interest, including:
Monitoring of vital parameters can include several of the ones mentioned above, and most commonly include at least blood pressure and heart rate, and preferably also pulse oximetry and respiratory rate. Multimodal monitors that simultaneously measure and display the relevant vital parameters are commonly integrated into the bedside monitors in critical care units, and the anesthetic machines in operating rooms. These allow for continuous monitoring of a patient, with medical staff being continuously informed of the changes in general condition of a patient. Some monitors can even warn of pending fatal cardiac conditions before visible signs are noticeable to clinical staff, such as atrial fibrillation or premature ventricular contraction.

Medical monitor

A medical monitor or physiological monitor is a medical device used for monitoring. It can consist of one or more sensors, processing components, display devices, as well as communication links for displaying or recording the results elsewhere through a monitoring network.

Components

Sensor

Sensors of medical monitors include biosensors and mechanical sensors.

Translating component

The translating component of medical monitors is responsible for converting the signals from the sensors to a format that can be shown on the display device or transferred to an external display or recording device.

Display device

Physiological data are displayed continuously on a CRT, LED or LCD screen as data channels along the time axis, They may be accompanied by numerical readouts of computed parameters on the original data, such as maximum, minimum and average values, pulse and respiratory frequencies, and so on.
Besides the tracings of physiological parameters along time, digital medical displays have automated numeric readouts of the peak and/or average parameters displayed on the screen.
Modern medical display devices commonly use digital signal processing, which has the advantages of miniaturization,, and multi-parameter displays that can track many different vital signs at once.
Old analog patient displays, in contrast, were based on oscilloscopes, and had one channel only, usually reserved for electrocardiographic monitoring. Therefore, medical monitors tended to be highly specialized. One monitor would track a patient's blood pressure, while another would measure pulse oximetry, another the ECG. Later analog models had a second or third channel displayed in the same screen, usually to monitor respiration movements and blood pressure. These machines were widely used and saved many lives, but they had several restrictions, including sensitivity to electrical interference, base level fluctuations and absence of numeric readouts and alarms.

Communication links

Several models of multi-parameter monitors are networkable, i.e., they can send their output to a central ICU monitoring station, where a single staff member can observe and respond to several bedside monitors simultaneously. Ambulatory telemetry can also be achieved by portable, battery-operated models which are carried by the patient and which transmit their data via a wireless data connection.
Digital monitoring has created the possibility, which is being fully developed, of integrating the physiological data from the patient monitoring networks into the emerging hospital electronic health record and digital charting systems, using appropriate health care standards which have been developed for this purpose by organizations such as IEEE and HL7. This newer method of charting patient data reduces the likelihood of human documentation error and will eventually reduce overall paper consumption. In addition, automated ECG interpretation incorporates diagnostic codes automatically into the charts. Medical monitor's embedded software can take care of the data coding according to these standards and send messages to the medical records application, which decodes them and incorporates the data into the adequate fields.
Long-distance connectivity can avail for telemedicine, which involves provision of clinical health care at a distance.

Other components

A medical monitor can also have the function to produce an alarm to alert the staff when certain criteria are set, such as when some parameter exceeds of falls the level limits.

Mobile appliances

An entirely new scope is opened with mobile carried monitors, even such in sub-skin carriage. This class of monitors delivers information gathered in body-area networking to e.g. smart phones and implemented autonomous agents.

Interpretation of monitored parameters

Monitoring of clinical parameters is primarily intended to detect changes in the clinical status of an individual. For example, the parameter of oxygen saturation is usually monitored to detect changes in respiratory capability of an individual.

Change in status versus test variability

When monitoring a clinical parameters, differences between test results can reflect either an actual change in the status of the condition or a test-retest variability of the test method.
In practice, the possibility that a difference is due to test-retest variability can almost certainly be excluded if the difference is larger than a predefined "critical difference". This "critical difference" is calculated as:
, where:
For example, if a patient has a hemoglobin level of 100 g/L, the analytical variation is 1.8% and the intra-individual variability CVi is 2.2%, then the critical difference is 8.1 g/L. Thus, for changes of less than 8 g/L since a previous test, the possibility that the change is completely caused by test-retest variability may need to be considered in addition to considering effects of, for example, diseases or treatments.
Critical differences for other tests include early morning urinary albumin concentration, with a critical difference of 40%.

Techniques in development

The development of new techniques for monitoring is an advanced and developing field in smart medicine, biomedical-aided integrative medicine, alternative medicine, self-tailored preventive medicine and predictive medicine that emphasizes monitoring of comprehensive medical data of patients, people at risk and healthy people using advanced, smart, minimally invasive biomedical devices, biosensors, lab-on-a-chip and advanced computerized medical diagnosis and early warning tools over a short clinical interview and drug prescription.
As biomedical research, nanotechnology and nutrigenomics advances, realizing the human body's self-healing capabilities and the growing awareness of the limitations of medical intervention by chemical drugs-only approach of old school medical treatment, new researches that shows the enormous damage medications can cause, researchers are working to fulfill the need for a comprehensive further study and personal continuous clinical monitoring of health conditions while keeping legacy medical intervention as a last resort.
In many medical problems, drugs offer temporary relief of symptoms while the root of a medical problem remains unknown without enough data of all our biological systems
. Our body is equipped with sub-systems for the purpose of maintaining balance and self healing functions. Intervention without sufficient data might damage those healing sub systems. Monitoring medicine fills the gap to prevent diagnosis errors and can assist in future medical research by analyzing all data of many patients.
Capsule endoscopy

Examples and applications

The development cycle in medicine is extremely long, up to 20 years, because of the need for U.S. Food and Drug Administration approvals, therefore many of monitoring medicine solutions are not available today in conventional medicine.
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;Blood glucose monitoring
;Stress monitoring
;Serotonin biosensor
;Continuous blood test based nutrition
;Psychiatrist-on-a-chip
;Epilepsy monitoring
;Toxicity monitoring