Midtown High School appears in Ultimate Spider-Man. Just like the mainstream comics, it depicts Peter, Flash and Liz Allan as students. Unlike the mainstream comic book, characters such as Gwen Stacy, Eddie Brock, Mary Jane Watson and Harry Osborn also debut in the high school instead of the Empire State University. X-Men member Kitty Pryde is also depicted as attending the high school. The comic also depicts a new character called Kenny "King Kong" McFarlane, who is depicted as best friend of Flash in high school. Mark Raxton is also depicted as a student who attends Midtown High school.
Midtown High School appears in Spider-Man Loves Mary Jane. Student faculty includes Peter Parker, Mary Jane Watson, Liz Allan, Flash Thompson, Harry Osborn and Gwen Stacy. Felicia Hardy appears as a tough transfer student. Jessica Jones is a former friend of Mary Jane's who became a goth. Luke Cage has a brief cameo where he flirts with Mary Jane. Ned Leeds and Betty Brant are older students with the former being Mary Jane's ex. A new character named Lindsay Leighton is the school's drama queen who envies Mary Jane's acting ability.
In other media
Television
Midtown High School is a major recurring setting in The Spectacular Spider-Man. Unlike most other depictions, this version of the school appeared to be located in Midtown Manhattan judging from Spider-Man's commute in an earlier episode. The series debuts both Principal Davis and Aaron Warren in other media. Other staff included are the class's coach Coach Smith, and the theater teacher St. John Devereaux. The recurring students depicted in the series are Peter Parker, Gwen Stacy, Flash Thompson, Liz Allan, Sally Avril, Kenny "King Kong", Hobie Brown, Rand Robertson, Glory Grant, Harry Osborn, Mary Jane Watson, Sha Shan Nguyen and Mark Allan. Eddie Brock was also a graduate of the school before attending Empire State University. The series also debuts students from the comics Seymour O'Reilly and "Tiny" McKeever.
Midtown High School appears in Ultimate Spider-Man. S.H.I.E.L.D. Director Nick Fury appointed S.H.I.E.L.D. Agent Phil Coulson to be the Acting Principal. Another notable staff member is a janitor named Stan who is one of the original S.H.I.E.L.D. Agents. During Season Three, Stan becomes the Acting Principal at the time when Phil Coulson was away on a special mission.
Midtown High School is featured in Marvel's Spider-Man. Its known teachers include assistant chemistry teacher Anna Maria Marconi and science teacher Sal Salerno.
Film
Midtown High School appears in the 2002 feature filmSpider-Man, where Parker is depicted as a high school senior until graduation. Both he and Harry Osborn appear as best friends while Flash Thompson is depicted as the class bully. Instead of Liz Allan, Mary Jane Watson is depicted as Peter's high school crush and once girlfriend of Flash. It is mentioned that Harry had to go there after flunking out of many private schools.
Midtown School of Science and Technology also appears in ', which takes place in the Marvel Cinematic Universe, with Peter as a sophomore. His classmates include Ned Leeds, Flash Thompson, Betty Brant, Jason Ionello, Liz Toomes, Cindy Moon, Seymour O'Reilly, Tiny McKeever, Charles Murphy, Abe Brown, Sally Avril, and a new character named Michelle Jones. Liz is a senior and Flash is a sophomore as opposed to both of them being in the same grade as Peter and his friends. In this version MSHS is a STEM school with many of Peter's classmates, who are usually depicted as being unenthusiastic about science, being depicted as science graduates. Faculty includes Roger Harrington ; Coach Wilson, Mr. Cobbwell, Monica Warren and Barry Hapgood, the shop class teacher. The school's principal is Principal Morita, who is shown to be a descendant of Howling Commandos member Jim Morita, also portrayed by Choi in previous MCU media.
Several students of Midtown School including Peter, Ned, Sally, Cindy and Tiny appear in ' where they are on a field trip to MOMA and suddenly spot a Q-Ship piloted by Ebony Maw, which prompts Peter to go and investigate.
In ', the film introduces teacher Julius Dell as well as students Brad Davis, Zach Cooper, and Josh Scarino'''. Other students include Zoha Rahman, Yasmin Mwanza, Tyler Luke Cunningham, and Sebastian Viveros whose characters are named after them.
