The Mid-South Conference is an athletic conference affiliated with the NAIA. Member institutions are located in Alabama, Kentucky, Mississippi, Ohio, Tennessee, and Virginia. The Mid-South Conference has nine full members: Campbellsville, Cumberland, Cumberlands, Georgetown College, Lindsey Wilson, Life, Pikeville, Shawnee State, and Thomas More. Seven of these members sponsor football; Life and Shawnee State do not. The Mid-South Conference also has six associate members that compete primarily in other conferences. Faulkner, Kentucky Christian, Union and recently former member Bluefield are associate members of the MSC for football and men's volleyball, Bethel is an associate member of the MSC for football and archery, and Reinhardt is an associate member of the MSC for football and men's volleyball. This gave the conference 13 members for football. In the spring of 2016, the conference expanded to 20 members, adding the six football members of The Sun Conference, as well as Faulkner University for football, On January 4, 2018, the conference added Keiser University for football, and St. Thomas announced in July they were joining the conference for football in 2019. Another Sun Conference member, Florida Memorial in Miami Gardens, Florida joined the MSC as an affiliate member for football in 2020, after re-adding the sport. Also in 2020, Bethel became a Mid-South full member, brought track and field back to the MSC, and transferred all sports other than football and archery to the conference; additionally, Freed–Hardeman and Martin Methodist also joined Mid-South. In April 2018, Thomas More University, which had been an NAIA member before moving to NCAA Division III in 1990, announced that it had been formally invited to rejoin the NAIA effective in 2019–20 as a member of the Mid-South Conference. The school, while acknowledging that it was considering this move, denied published reports that it had accepted the invitation. Thomas More eventually confirmed in July that it would join the Mid-South in 2019. The league is headquartered in Louisville, Kentucky, and the commissioner is Eric Ward.
Member schools
Full members
Bethel — for archery and football, left the Mid-South after the 1996 fall season ; later re-joined in the 2003 fall season. In the 2020 fall season, Bethel moved track & field back to the Mid-South after initially joining as an affiliate from 2007 to 2013, and transferred all other sports to the conference.
Cumberland — left the Mid-South in 2002, and re-joined in 2012.
Affiliate members
Beginning with the 2017 season, The Sun Conference and Mid-South merged its football conferences into the largest football conference in college sports. Edward Waters was previously a full member of the Sun Conference from 2006 to 2010 and a football affiliate member from 2014 to 2016 seasons. Edward Waters left after the 2018 football season. The divisions are divided [|below].
Former members
Former affiliate members
Sports
Member teams compete in 24 sports: 12 men's, 10 women's and 2 mixed.
