In 1995, West joined the cast of the CBS soap opera As the World Turns in the role of Carly Tenney. She held the role from April 11, 1995 to May 8, 1996. West later returned to the role on September 10, 1997, remaining on the series, until its television finale on September 17, 2010. West has received a number of honors for her portrayal of Carly, including nominations for the Soap Opera Digest Award for Outstanding Villainess in 1996, for Outstanding Younger Lead Actress 1999 and 2000, for Favorite Couple in 2001, an award which she shared with co-star Michael Park. She received a Daytime Emmy Award nomination for Outstanding Supporting Actress in a Drama Series in 2001 and 2002. West also received three nominations for the Daytime Emmy Award for Outstanding Lead Actress in a Drama Series in 2004, 2008 and 2009; only winning twice, once in 2007 and in 2010. At the 32nd Daytime Emmy Awards, West and Park received a nomination for the Special Fan Award for Most Irresistible Combination. It was announced in August 2010 that West would join the CBS soap opera, The Young and the Restless, as the third actress to portray Diane Jenkins. West began work in the role on September 1, 2010, and made her first appearance on the show on October 8, 2010. In May 2011, CBS Soaps Indepth confirmed West had been let go from the soap after only several months on-air. In April 2013, it was announced that West would join the ABC soap opera General Hospital, in a top-secret role. On April 24, 2013, West was confirmed to have joined the cast in the newly created role of Ava Jerome, and first appeared on May 8. West's portrayal of Ava has been met with critical acclaim, having earned her a nomination for the Daytime Emmy Award for Outstanding Lead Actress in a Drama Series in 2015, her first for her portrayal of Ava and sixth over-all in the category. She later won in the category on April 26, 2015. In 2014, West made her first appearance in the feature film, Come Back to Me, which served as an adaption of the novel, The Resurrectionist.
Personal life
West has been married twice: to director Jonathan Knight from 1995 to 1999, and to former As the World Turns co-star Scott DeFreitas since January 22, 2000. West has five children. One of her children, Joe West, is a Broadway actor.