Kreuzer played for St Mary's Greensborough Junior Football Club, part of the Yarra Junior Football League, in Melbourne's north as a junior, before moving to the Northern Knights to play under-18s football in the TAC Cup in 2006 and 2007. Kreuzer established himself as both the team's No. 1 ruckman and as a key forward during that time, scoring 51 goals in his 33 games with the Knights. In 2007, he won the Morrish Medal and the Knights' best and fairest, and he was selected in the Victorian Metropolitan and All-Australian under-18s teams, and in the TAC Cup Teams of the Year in both 2006 and 2007. Noted for possessing a level of agility and endurance unusual for a player of his size, Kreuzer was widely expected to be selected early in the 2007 AFL Draft. He was selected by Carlton with its priority draft pick in the draft; Carlton received that draft pick only after losing its final round match against in 2007, a controversial match which became known as the Kreuzer Cup.
Professional career
Kreuzer made his AFL debut in Round 3 of the 2008 season against Essendon at the MCG on 5 April2008, impressing on debut and scoring a goal with his first kick. He played largely as the second ruckman through the early part of the season. He earned a NAB Rising Star nomination in his ninth game, after moving into the forward-line in the final quarter and scoring three goals, which helped Carlton overcome a 30-point deficit in wet conditions; he would ultimately poll eleven votes to finish fourth for the award. Towards the end of the season, Kreuzer was playing both ruck and forward roles. He was noted for his accuracy in front of goal, scoring 13 goals and only one behind in his debut season. Kreuzer played all twenty-three games in his second season, again sharing ruck duties and spending some time in the forward-line, again scoring thirteen goals. He finished fifth in the John Nicholls Medal. Kreuzer continued as one of the club's top two ruckmen in 2010, and he played his 50th AFL game in Round 7. In Round 13, 2010, after 56 consecutive games from debut, Kreuzer ruptured his anterior cruciate ligament after landing awkwardly in a marking contest. He had a conventional knee reconstruction, and missed eleven months of football, returning to VFL football in May 2011 and to Carlton in Round 12, 2011. He played every game for the rest of the 2011 home-and-away season, but after twelve months out of the game was well below his best, polling best-and-fairest votes only once. In 2017, Kreuzer had a career best season only missing one game. He was selected in the initial 40 man All Australian squad and finished 3rd in Carlton's best and fairest. Before the beginning of the 2018 season it was announced that Kreuzer would be part of Carlton's new leadership group for the first time in his career. At the end of the 2018 season, Kreuzer had relinquished his position in the leadership group, along with Alex Silvagni and Lachlan Plowman.
Personal life
His father is of Dutch heritage. Outside of football, Kreuzer is a civil engineer.