Moore began his DJ career in 1983 playing at the fashionable London club, 'The Mud Club', run by Philip Sallon. Later that year as his popularity grew he was given a slot at the alternative, mixed/gay night 'Asylum' at Heaven nightclub which later became 'Pyramid' at Heaven. He soon became a successful DJ often appearing in Time Out's 'best DJ' polls. As well as playing new-wave electronic dance music, such as Yello, Cabaret Voltaire, Soft Cell and New Order; Moore was one of the first DJs in the UK to support and play Chicago House music and DetroitTechno. In 1988 Moore launched S'Express with co-writer/co-producer Pascal Gabriel. The first single "Theme From S'Express" went to number 1 in the UK Singles Chart, and is credited by Muzik magazine as 'kick starting the UK house scene'. This was followed up with "Superfly Guy" which reached number 5 in the UK Chart. Moore and William Orbit formed a friendship, when Moore asked Orbit to remix the S'Express hit, "Hey Music Lover", and the duo worked together mixing Prince's "Batdance", "Electric Chair" and "The Future" plus Malcolm McLaren's "Deep in Vogue", "Something's Jumpin' In Your Shirt" and "Call A Wave". Moore also had a working relationship with engineer Mark McGuire. He would feature up-and-coming Billie Ray Martin as vocalist on "Hey Music Lover", giving her early exposure before her band, Electribe 101, released its debut album. An admirer of the composer Philip Glass, Moore asked Glass to remix "Hey Music Lover", which the composer did in singular style. A friendship was also formed with Carl Craig when he first came to London aged 19 and Craig worked on the second S'Express album "Intercourse". Moore also had made a cameo appearance as a pirate radio DJ on Bomb the Bass's debut album Into The Dragon. Moore was heard playing the 'fluffy bagel mix' of "Superfly Guy" on "Get Outta Bed Radio!" That mix can by found on the Hip Hop and Rapping in the Housecompilation released in the late 1980s. Other cameos include appearing on the French & SaundersTV show as part of the She Rappers sketch, which can be seen on 'The Best of French And Saunders' DVD. During 2002, he was involved with the Needledust project with Robert Michael and Tim Southgate. In 2005, Moore set up the record label Umami Records. From 2005 onwards Moore has released new music and remixes under the monikers Mark Moore & Eon, Mark Moore & Kinky Roland and UltraViva. Moore has also remixed Prince, Malcolm McLaren, Seal, Erasure, Dead Or Alive, Divine, Boystown Gang, The Real Thing, Randy Crawford, The B-52's, Soft Cell, the electro pop band, Temposhark, Unklejam, Client, Mlle Caro & Frank Garcia, Next Door But One and Chanty Poe, amongst others. In 2008 S'Express came out of cryogenic slumber and released "Stupid Little Girls" on the Kitsuné label to mark the 20-year anniversary of the second summer of love and to 'confuse the history books'. Moore also writes articles for magazines. He has a weekly music column with Princess Julia in QX International. Published articles include: interviews with John Waters and Siouxsie Sioux ; a Russ Meyer feature for Fused; 'Acid House London: The Mark Moore Experience' for Clash Magazine; 'Punk Rock Saved My Life' for Super Super.