Born on 20 May 1938 in Copenhagen, Lone Herman Koppel was the daughter of the composer Herman David Koppel and Edel Vibeke Clausen-Bruun. She married three times: on 15 June 1961 with the editor Erik Cosman Lindgren, divorced in 1969; on 30 April 1969 with the pianist and opera director John Winther, divorced in 1979; and on 23 July 1983 with the Swedish opera singer Björn Asker. She has three children: Mie, Thomas Peter and Nikolaj. Brought up in a musical family, she sang from an early age and by the time she was 11, could accompany herself while singing songs by Brahms and Schubert. She studied at the Royal Danish Conservatoire under Dora Sigurdsson before specializing in opera at the Royal Theatre's Opera Academy. While studying, she appeared in public with her father but it was in September 1962 that she made her mark playing Musetta in Puccini's La bohème. Two years later, together with Ib Hansen, she achieved even greater success as Tosca in a television production directed by Holger Boland. From 1964 to 1966, she joined the Kiel Opera but remained the most popular operatic soprano in Denmark as she performed leading roles such as Santuzza in Cavalleria rusticana, Elisabeth in Tannhäuser and Senta in The Flying Dutchman and once again as Tosca when the opera was again presented by the Royal Theatre in 1967. Other successes included her roles in Simone Boccanegra, Eugene Onegin, and Il trovatore. In the 1960s and early 1970s, she was Copenhagen's most productive opera singer, performing not only traditional roles but also participating in the new repertoire, for example as Marie in Berg's Wozzeck or playing the title role in Shostakovich's Katerina Ismailova. In 1973, together with her husband John Winther, she joined the Australian Opera where, in addition to her Danish roles, she sang Jenny in Weill's Mahagonny. On returning to Copenhagen in 1978, her new roles included Lady Macbeth in Verdi's Macbeth and the title role in Richard Strauss's Elektra , which she also performed for her 25th anniversary at the Royal Theatre in 1987. Although her voice began to suffer in her old age, she still received acclaim for playing the comic role of Fata Morgana in Prokofiev's The Love for Three Oranges. Koppel was invited by Poul Jørgensen to direct Peter Heise's Drot og marsk at the Royal Theatre in 1993. During her career, she has also performed in concerts throughout Scandinavia as well as in England, Germany, the Netherlands and New Zealand.