List of psychoactive plants


A list of plants that are used as psychoactive drugs. Some of them have been used entheogenically for millennia. The plants are listed according to the substances they contain.

''Cannabis''

Cannabis is a popular psychoactive plant that is often used medically and recreationally. The psychoactive substance in Cannabis, THC, is unique in that it contains no nitrogen and is not an indole, tryptamine, phenethylamine, anticholinergic, or a dissociative drug. Cannabis plants tend to vary, with different strains producing dynamic balances of cannabinoids yielding markedly different effects. Popular strains are often hybrids of Cannabis sativa and Cannabis indica.
Some universities and research firms currently study the medicinal effects of cannabis. Many jurisdictions have laws regulating or prohibiting the sale and use of medical and recreational cannabis.

Tryptamines

Many of the psychedelic plants contain dimethyltryptamine, which is either snorted, vaporized, or drunk with MAOIs. It cannot simply be eaten as it is not orally active without an MAOI and it needs to be extremely concentrated to be vaporized.

[Acanthaceae]

Species, Alkaloid content, where given, refers to dried material
Shibam, DMT
aff. litorale

1,2,3,4-Tetrahydro-6-methoxy-2,9-dimethyl-beta-carboline, Plant, 1,2,3,4-Tetrahydro-6-methoxy-2-methyl-beta-carboline, Plant, 5-Methoxy-N,N-dimethyltryptamine, Bark, 5-Methoxy-N-methyltryptamine, Bark, Bufotenin, plant, beans, Bufotenin N-oxide, Fruit, beans, N,N-Dimethyltryptamine-oxide, Fruit
Some Graminae species contain gramine, which can cause brain damage, other organ damage, central nervous system damage and death in sheep.
None of the above alkaloids are said to have been found in Phalaris californica, Phalaris canariensis, Phalaris minor and hybrids of P. arundinacea together with P. aquatica.

[Polygonaceae]

Species, Alkaloid Content - Alkaloid Content
s are "reversible" MAO-A inhibitors. They are found in some plants used to make Ayahuasca. In high doses the harmala alkaloids are somewhat hallucinogenic on their own. β-carboline is a benzodiazepine receptor inverse agonist and can therefore have convulsive, anxiogenic and memory enhancing effects.

[Apocynaceae]

SubstancePlantComment
AsaroneAcorus calamusAsarone
YohimbineAlchornea floribundaYohimbine
ArecolineAreca catechuAreca nut or betel
Unknown
Argemone mexicana
Used by Chinese residents of Mexico during the early 20th century as a legal substitute for opium and currently smoked as a marijuana substitute.

Ergine

Argyreia nervosa
Seeds contain high amounts of ergine, often 50-150X the amounts found in Ipomoea violacea.
ThujoneArtemisia absinthiumAdditive to absinthe. Also called "wormwood"
UnknownAsiminia TrilobaL.Identical alkaloid to morphine
Tropane alkaloidsAtropa belladonnaDeadly nightshade
Tropane alkaloidsBrugmansiaAngel's trumpets
Unknown
Calea zacatechichi
Produces vivid dreams after smoking. It is also employed by the Chontal people as a medicinal herb against gastrointestinal disorders, and is used as an appetizer, cathartic anti-dysentery remedy, and as a fever-reducing agent. Its psychedelic properties do not become apparent until the user is asleep.
CaffeineCamellia sinensisTea leaves, tea, native to Asia

Cathinone

Catha edulis
Khat
VincristineCatharanthus roseusCatharanthus roseus is "hallucinogenic."
UnknownCestrum nocturnumNight-blooming jasmine
CaffeineCoffea arabicaCoffee beans, coffee, native to Africa
CaffeineColaCola or kola nut, traditional additive to cola, native to Africa
Unknown
Coleus
Unknown

Bulbocapnine

Corydalis solida, cava
Bulbocapnine, Nantenine, Tetrahydropalmatine
Tropane alkaloidsDaturaThorn apple, devil's trumpets, loco weed, Jimson weed
CytisineDermatophyllumMescal bean
UnknownDesfontainia spinosaCauses visions
NicotineDuboisia hopwoodiiPituri
UnknownEntada rheediiAfrican dream herb
EphedrineEphedra sinicaEphedra
CocaineErythroxylum cocaCoca. Widely used illegal stimulant, produces hallucination in overdose, native to South America
UnknownFittonia albivenisNerve or mosaic plant
Unknown
Foeniculum vulgare
Unknown

Himbacine
Galbulimima belgraveanaGalbulimima belgraveana is rich in alkaloids and twenty-eight alkaloids have been isolated including himbacine.

Glaucine

Glaucium flavum
Glaucine
UnknownHeimia myrtifoliaAuditory
UnknownHeimia salicifoliaAuditory
LobelineHippobroma longifloraStar of Bethlehem
HyperforinHypericum perforatumSaint John's wort
Tropane alkaloidsHyoscyamusHenbane
UnknownIlex guayusaIlex guayusa is used as an additive to some versions of Ayahuasca. According to the Ecuadorian indigenous, it is also slightly hallucinogenic on its own, when drunk in high enough quantities.
Ergine
Ipomoea tricolor & Ipomoea violacea
Ergine in seeds; up to 0.12% total
UnknownJusticia pectoralisUnknown
Lactucarium
Lactuca virosa
Lactucarium

Lagochilin
Lagochilus inebriansLagochilin is thought to be responsible for the sedative, hypotensive and hemostatic effects of this plant.

Pukateine

Laurelia novae-zelandiae
Pukateine
UnknownRollinia mucosaRollinia mucosa is said to be narcotic

Leonurine

Leonotis leonurus
Both leaves and flowers contain Leonurine.

Leonurine

Leonotis nepetifolia
Both leaves and flowers contain Leonurine.
LobelineLobelia inflataIndian tobacco
Unknown
Magnolia virginiana
Tropane alkaloidsMandragora officinarumMandrake
ErgineSome Mirabilis spp.Possibly contains ergine
MitragynineMitragyna speciosaKratom
MyristicinMyristica fragransNutmeg
AporphineNelumbo nuciferaSacred lotus
NepetalactoneNepeta catariaCatnip
NicotineNicotiana tabacumTobacco. Can cause hallucination in very large doses

Aporphine

Nymphaea caerulea
Blue lotus or lily. Recent studies have shown Nymphaea caerulea to have psychedelic properties, and may have been used as a sacrament in ancient Egypt and certain ancient South American cultures. Dosages of 5 to 10 grams of the flowers induces slight stimulation, a shift in thought processes, enhanced visual perception, and mild closed-eye visuals. Nymphaea caerulea is related to, and possesses similar activity as Nelumbo nucifera, the Sacred Lotus. Both Nymphaea caerulea and Nelumbo nucifera contain the alkaloids nuciferine and apomorphine, which have been recently isolated by independent labs.
These psychoactive effects make Nymphaea caerulea a likely candidate for the lotus plant eaten by the mythical Lotophagi in Homer's Odyssey.
Used in aromatherapy, Nymphaea caerulea is purported to have a "divine" essence, bringing euphoria, heightened awareness and tranquility.
Other sources cite anti-spasmodic and sedative, purifying and calming properties.
HeliaminePachycereus pringleiLargest cactus in the world. Heliamine bears some similarities to mescaline
GinsenosidesPanaxGinseng
MorphinePapaver somniferumOpium. Widely used analgesic, native to the Old World
ChrysinPassifloraPassion flower
UnknownPhytolacca americanaL.Naroctic and toxic when root is consumed.
YohimbinePausinystalia johimbeYohimbe
UnknownPedicularis densifloraIndian warrior

Kavalactones

Piper methysticum
Kavalactones
ErgineRivea corymbosaSeeds contain ergine, lysergol, and turbicoryn; lysergic acid alkaloids up to 0.03%

Salvinorin A

Salvia divinorum
Salvinorin A, 0.89-3.87 mg/g, also Salvinorin B and Salvinorin C
MesembrineSceletium tortuosumKanna
BaicaleinScutellariaSkullcaps
Unknown
Silene capensis
Produces vivid dreams after smoking.
Unknown
Tagetes lucida
Anethole, Chavicol, Coumarin, Estragole, Isorhamnetin, Methyleugenol, Quercitin

Ibogaine

Tabernanthe iboga
Ibogaine in root bark

Ibogaine

Tabernanthe orientalis
Ibogaine in root leaves
Voacangine
Tabernaemontana divaricata
Voacangine is similar to ibogaine. It potentiated effect of barbituarates which may possibly mean voacangine is psychoactive.

Ibogaine

Tabernanthe pubescens
Ibogaine and similar alkaloids

Ibogaine

Tabernaemontana sp.
Ibogaine
CaffeineTheobroma cacaoCocoa or cacao bean, chocolate, native to the Americas

Ibogaine

Trachelospermum jasminoides
Ibogaine, coronaridine, voacangine, apparicine, conoflorine, and 19-epi-voacangarine
Damianin
Turnera diffusa
Damianin
ActinidineValeriana officinalisValerian
VincamineVinca minorVincamine
VoacangineVoacanga africanaVoacangine is similar to ibogaine
UnknownZornia latifoliaZornia latifolia is mentioned in Food of the Gods as "an hallucinogenic substitute for cannabis". It is nicknamed Maconha brava because locals use it as a cannabis substitute.