List of number-one hits of 1966 (Mexico)
This is a list of the songs that reached number one in Mexico in 1966, according to Billboard magazine with data provided by Audiomusica.
Chart history
| Issue Date | Song | Artist | Ref. |
| January 1 | "Es Lupe" | :es:Los Johnny Jets|Los Johnny Jets | |
| January 8 | "Es Lupe" | :es:Los Johnny Jets|Los Johnny Jets | |
| January 15 | "Es Lupe" | :es:Los Johnny Jets|Los Johnny Jets | |
| January 22 | "Es Lupe" | :es:Los Johnny Jets|Los Johnny Jets | |
| January 29 | "Es Lupe" | :es:Los Johnny Jets|Los Johnny Jets | |
| February 5 | "Es Lupe" | :es:Los Johnny Jets|Los Johnny Jets | |
| February 12 | "Es Lupe" | :es:Los Johnny Jets|Los Johnny Jets | |
| February 19 | "Es Lupe" | :es:Los Johnny Jets|Los Johnny Jets | |
| February 26 | "Por las calles de México" | Sonora Santanera | |
| March 5 | "Es Lupe" | Los Johnny Jets | |
| March 12 | "Mazatlán" | :es:Mike Laure|Mike Laure | |
| March 19 | "Es Lupe" | Los Johnny Jets | |
| March 26 | "La banda borracha" | Mike Laure | |
| April 2 | "Senza fine" | The Brass Ring | |
| April 9 | "La banda borracha" | Mike Laure | |
| April 16 | "La banda borracha" | Mike Laure | |
| April 30 | "La banda borracha" | Mike Laure | |
| May 7 | "La banda borracha" | Mike Laure | |
| May 14 | "La banda borracha" | Mike Laure | |
| May 21 | "La banda borracha" | Mike Laure | |
| May 28 | "Una limosna" | Javier Solís | |
| June 4 | "Una limosna" | Javier Solís | |
| June 11 | "Una limosna" | Javier Solís | |
| June 18 | "Una limosna" | Javier Solís | |
| June 25 | "Amigo organillero" | Javier Solís | |
| July 2 | "Amigo organillero" | Javier Solís | |
| July 9 | "Amigo organillero" | Javier Solís | |
| July 16 | "Amigo organillero" | Javier Solís | |
| July 23 | "Amigo organillero" | Javier Solís | |
| July 30 | "El despertar" | Marco Antonio Muñiz | |
| August 6 | "El despertar" | Marco Antonio Muñiz | |
| August 13 | "El despertar" | Marco Antonio Muñiz | |
| August 20 | "El despertar" | Marco Antonio Muñiz | |
| August 27 | "El despertar" | Marco Antonio Muñiz | |
| September 3 | "Mi razón" | Sonora Santanera | |
| September 10 | "Mi razón" | Sonora Santanera | |
| September 17 | "Mi razón" | Sonora Santanera | |
| October 1 | "Mi razón" | Sonora Santanera | |
| October 8 | "Senza fine" | The Brass Ring | |
| October 15 | "La banda borracha" | Mike Laure | |
| October 22 | "La banda borracha" | Mike Laure | |
| October 29 | "Mi razón" | Sonora Santanera | |
| November 5 | "Brasilia" | Tony Mottola | |
| November 19 | "Fuiste a Acapulco" | :es:Los Apson|Los Apson | |
| November 26 | "Fuiste a Acapulco" | :es:Los Apson|Los Apson | |
| December 10 | "Brasilia" | Tony Mottola | |
| December 17 | "El botones" | Sonora Santanera | |
| December 24 | "Senza fine" | The Brass Ring | |
| December 31 | "Fuiste a Acapulco" | Los Apson |