List of number-one dance singles of 1995 (U.S.)
These are the Billboard magazine Hot Dance Club Play number one hits of 1995.
| Issue date | Song | Artist | Reference |
| January 7 | "Melody of Love " | Donna Summer | |
| January 14 | "Melody of Love " | Donna Summer | |
| January 21 | "Melody of Love " | Donna Summer | |
| January 28 | "I Get Lifted" | Barbara Tucker | |
| February 4 | "Call Me" | Deee-Lite | |
| February 11 | "Don't Bring Me Down" | Spirits | |
| February 18 | "Don't Bring Me Down" | Spirits | |
| February 25 | "Everlasting Love" | Gloria Estefan | |
| March 4 | "Everlasting Love" | Gloria Estefan | |
| March 11 | "Come Back" | Londonbeat | |
| March 18 | "Your Loving Arms" | Billie Ray Martin | |
| March 25 | "Your Loving Arms" | Billie Ray Martin | |
| April 1 | "Never Get Enough" | Waterlilies | |
| April 8 | "Atomic" | Blondie | |
| April 15 | "Heartbeat" | Jimmy Somerville | |
| April 22 | "The Bomb! " | The Bucketheads | |
| April 29 | "The Bomb! " | The Bucketheads | |
| May 6 | "Respect" | Judy Cheeks | |
| May 13 | "Bedtime Story" | Madonna | |
| May 20 | "Keep in Touch " | Shades of Love featuring Meli'sa Morgan | |
| May 27 | "What Hope Have I" | Sphynx | |
| June 3 | "Open Your Heart" | M People | |
| June 10 | "I'm Ready" | Size 9 | |
| June 17 | "Too Many Fish" | Frankie Knuckles featuring Adeva | |
| June 24 | "Too Many Fish" | Frankie Knuckles featuring Adeva | |
| July 1 | "You" | Staxx of Joy featuring Carol Leeming | |
| July 8 | "Space Cowboy" | Jamiroquai | |
| July 15 | "Scream" | Michael Jackson and Janet Jackson | |
| July 22 | "Scream" | Michael Jackson and Janet Jackson | |
| July 29 | "You Bring Me Joy" | Mary J. Blige | |
| August 5 | "As Long as You're Good to Me" | Judy Cheeks | |
| August 12 | "Relax" | Crystal Waters | |
| August 19 | "My Love Is for Real" | Paula Abdul | |
| August 26 | "Come and Get Your Love" | Real McCoy | |
| September 2 | "No More I Love You's" | Annie Lennox | |
| September 9 | "No More I Love You's" | Annie Lennox | |
| September 16 | "Everybody Be Somebody" | Ruffneck featuring Yavahn | |
| September 23 | "Everybody Be Somebody" | Ruffneck featuring Yavahn | |
| September 30 | "Everybody Be Somebody" | Ruffneck featuring Yavahn | |
| October 7 | "Turn It Out" | Labelle | |
| October 14 | "We Can Make It" | Moné | |
| October 21 | "Fantasy" | Mariah Carey | |
| October 28 | "Fantasy" | Mariah Carey | |
| November 4 | "Fantasy" | Mariah Carey | |
| November 11 | "Stay Together" | Barbara Tucker | |
| November 18 | "I'll Always Be Around" | C+C Music Factory featuring A.S.K. M.E. and Vic Black | |
| November 25 | "I'll Always Be Around" | C+C Music Factory featuring A.S.K. M.E. and Vic Black | |
| December 2 | "Take Me Higher" | Diana Ross | |
| December 9 | "Believe in Me" | Raw Stylus | |
| December 16 | "Reach" | Lil' Mo' Yin Yang | |
| December 23 | "Be My Lover" | La Bouche | |
| December 30 | "Be My Lover" | La Bouche |