List of highways numbered 53

Cambodia

• National Road 53

  Canada

• Alberta Highway 53

  India

• National Highway 53

  Japan

• Route 53

  Korea, South

• National Route 53

  Mexico

• Mexican Federal Highway 53

  New Zealand

• New Zealand State Highway 53

  Philippines

• National Route 53

  Turkey

• , a motorway in Turkey connecting with İskenderun, Hatay Province.

  United Kingdom

• British A53
• British M53

  United States

• Interstate 53
• U.S. Route 53
• Alabama State Route 53
• Arkansas Highway 53
• California State Route 53
• Colorado State Highway 53
• Connecticut Route 53
• Florida State Road 53
• * County Road 53
• * County Road 53
• Georgia State Route 53
• Idaho State Highway 53
• Illinois Route 53
• Indiana State Road 53
• Iowa Highway 53
• K-53
• Kentucky Route 53
• Louisiana Highway 53
• * Louisiana State Route 53
• Maryland Route 53
• Massachusetts Route 53
• M-53
• County Road 53
• * County Road 53
• * County Road 53
• Mississippi Highway 53
• Missouri Route 53
• Nebraska Highway 53
• * Nebraska Link 53A
• * Nebraska Link 53B
• * Nebraska Link 53C
• * Nebraska Link 53E
• Nevada State Route 53
• New Jersey Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• New Mexico State Road 53
• New York State Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• ** County Route 53A
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• * County Route 53
• ** County Route 53A
• * County Route 53
• * County Route 53
• * County Route 53
• North Carolina Highway 53
• North Dakota Highway 53
• Ohio State Route 53
• Oklahoma State Highway 53
• * Oklahoma State Highway 53A
• Oregon Route 53
• Pennsylvania Route 53
• South Carolina Highway 53
• South Dakota Highway 53
• Tennessee State Route 53
• Texas State Highway 53
• * Texas State Highway Spur 53
• * Farm to Market Road 53
• * Texas Park Road 53
• Utah State Route 53
• Vermont Route 53
• Virginia State Route 53
• West Virginia Route 53
• * West Virginia Route 53
• Wisconsin Highway 53

• Puerto Rico Highway 53