List of cytochrome P450 modulators


This is a list of cytochrome P450 modulators, or inhibitors and inducers of cytochrome P450 enzymes.
EnzymeInhibitorsInducers
CYP1A1
  • Certain foods
  • Insulin
  • Methylcholanthrene
  • Modafinil
  • Nafcillin
  • Omeprazole
  • Phenytoin
  • beta-Naphthoflavone
  • Tobacco
    • CYP2A6
  • Amiodarone
  • Amlodipine
  • Buprenorphine
  • Clofibrate
  • Clotrimazole
  • Desipramine
  • Disulfiram
  • Entacapone
  • Fenofibrate
  • Flavonoids
  • Gabapentin
  • Isoniazid
  • Ketoconazole
  • Letrozole
  • Methimazole
  • Methoxsalen
  • Metyrapone
  • Miconazole
  • Modafinil
  • Nicotine
  • Orphenadrine
  • Pilocarpine
  • Selegiline
  • Sulconazole
  • Tioconazole
  • Tranylcypromine
  • Barbiturates
  • Rifampicin
    • CYP2B6
  • Curcumin
  • Memantine
  • Orphenadrine
  • Thiotepa
  • Ticlopidine
  • Carbamazepine
  • Phenobarbital
  • Phenytoin
  • Rifampicin
    • CYP2C8
  • Gemfibrozil
  • Montelukast
  • Quercetin
  • Thiazolidinediones
  • Trimethoprim
  • Rifampicin
    • CYP2C9
  • Amiodarone
  • Apigenin
  • Chloramphenicol
  • Cimetidine
  • Cyclizine
  • Fenofibrate
  • Flavonoids
  • Fluconazole
  • Fluvastatin
  • Fluvoxamine
  • Isoniazid
  • Lovastatin
  • Miconazole
  • Modafinil
  • Nilutamide
  • Phenylbutazone
  • Probenecid
  • Promethazine
  • Quercetin
  • Sertraline
  • Sulfamethoxazole
  • Sulfaphenazole
  • Teniposide
  • Valproic acid
  • Voriconazole
  • Zafirlukast
  • Aprepitant
  • Bosentan
  • Enzalutamide
  • Phenobarbital
  • Phenytoin
  • Rifampicin
  • Secobarbital
  • St. Johns Wort
    • CYP2C19
  • Chloramphenicol
  • Cimetidine
  • Felbamate
  • Fluconazole
  • Fluoxetine
  • Fluvoxamine
  • Indomethacin
  • Isoniazid
  • JWH-018
  • Ketoconazole
  • Moclobemide
  • Modafinil
  • Probenecid
  • Proton pump inhibitors
  • Ticlopidine
  • Topiramate
  • Artemisinin
  • Aspirin
  • Carbamazepine
  • Enzalutamide
  • Norethisterone
  • Phenytoin
  • Prednisone
  • Rifampicin
    • CYP2D6
  • Amiodarone
  • Buprenorphine
  • Bupropion
  • Cannabidiol
  • Celecoxib
  • Chlorphenamine
  • Chlorpromazine
  • Cimetidine
  • Cinacalcet
  • Citalopram
  • Clemastine
  • Clomipramine
  • Cocaine
  • Diphenhydramine
  • Doxepin
  • Doxorubicin
  • Duloxetine
  • Escitalopram
  • Fluoxetine
  • Halofantrine
  • Haloperidol
  • Hydroxyzine
  • Hyperforin
  • Levomepromazine
  • Methadone
  • Methylphenidate
  • Metoclopramide
  • Mibefradil
  • Midodrine
  • Moclobemide
  • Niacin and its form – niacinamide, collectively called as vitamin B3
  • Paroxetine
  • Perphenazine
  • Promethazine
  • Quinidine
  • Ranitidine
  • Risperidone
  • Ritonavir
  • Sertraline
  • Terbinafine
  • Thioridazine
  • Ticlopidine
  • Tripelennamine
  • Zuclopenthixol
  • Dexamethasone
  • Glutethimide
  • Haloperidol
  • Rifampicin
    • CYP2E1
  • Cimetidine
  • Niacin and its form – niacinamide, collectively called as vitamin B3
    • CYP3A4
  • Amiodarone
  • Aprepitant
  • Bergamottin
  • Buprenorphine
  • Cafestol
  • Chloramphenicol
  • Cimetidine
  • Ciprofloxacin
  • Clarithromycin
  • Cobicistat
  • Delavirdine
  • Diltiazem
  • Dithiocarbamate
  • Domperidone
  • Erythromycin
  • Fluconazole
  • Fluvoxamine
  • Gestodene
  • Ginkgo biloba
  • Imatinib
  • Indinavir
  • Isoniazid
  • Itraconazole
  • Ketoconazole
  • Mibefradil
  • Mifepristone
  • Milk thistle
  • Nefazodone
  • Nelfinavir
  • Niacin and its form – niacinamide, collectively called as vitamin B3
  • Nilutamide
  • Norfloxacin
  • Orphenadrine
  • Piperine
  • Quercetin
  • Ranitidine
  • Ritonavir
  • Saquinavir
  • Star fruit
  • Telithromycin
  • Valerian
  • Valproic acid
  • Verapamil
  • Voriconazole
  • Barbiturates
  • Capsaicin
  • Carbamazepine
  • Efavirenz
  • Enzalutamide
  • Glucocorticoids
  • Modafinil
  • Nevirapine
  • Oxcarbazepine
  • Phenytoin
  • Pioglitazone
  • Quercetin
  • Rifabutin
  • Rifampicin
  • St. John's wort
  • Topiramate
  • Troglitazone
    • CYP4–51
  • See and instead for eicosanoid-specific CYP450s, including:
  • * CYP4F3
  • * CYP5A1
  • * CYP8A1
  • See the list of steroid metabolism modulators instead for steroid/sterol-specific CYP450s, including:
  • * CYP7A1
  • * CYP7B1
  • * CYP8B1
  • * CYP11A1
  • * CYP11B1
  • * CYP11B2
  • * CYP17A1
  • * CYP19A1
  • * CYP21A2
  • * CYP24A1
  • * CYP27A1
  • * CYP27B1
  • * CYP39A1
  • * CYP46A1
  • * CYP51A1