List of UK Dance Singles Chart number ones of 2001
These are The Official UK Charts Company UK Official Dance Chart number one hits of 2001.
| Issue date | Song | Artist |
| 6 January | "Coming Home" | K-Warren featuring Lee-O |
| 13 January | "Komodo " | Mauro Picotto |
| 20 January | "Camels" | Santos |
| 27 January | "Camels" | Santos |
| 3 February | "Boom Selection" | Genius Cru |
| 10 February | "Boom Selection" | Genius Cru |
| 17 February | "Synaesthesia " | The Thrillseekers featuring Sheryl Deane |
| 24 February | "American Dream" | Jakatta |
| 3 March | "American Dream" | Jakatta |
| 10 March | "The Vision" | Mario Più Presents DJ Arabesque |
| 17 March | "Piano Loco" | DJ Luck & MC Neat |
| 24 March | "Dirty Beats" | Roni Size/Reprazent |
| 31 March | "Joy" | Mark Ryder |
| 7 April | "Salsoul Nugget " | M&S presents The Girl Next Door |
| 14 April | "Happiness" | Sound De-Zign |
| 21 April | "How You Like Bass" | Norman Bass |
| 28 April | "Get Ur Freak On" | Missy Elliott |
| 5 May | "Love Is Not a Game" | J Majik featuring Kathy Brown |
| 12 May | "Back Up " | Wookie featuring Lain |
| 19 May | "Secrets" | Mutiny UK |
| 26 May | "Up Middle Finger" | Oxide & Neutrino |
| 2 June | "Do You Really Like It" | DJ Pied Piper and the Masters of Ceremonies |
| 9 June | "Just Can't Get Enough " | Eye to Eye featuring Taka Boom |
| 16 June | "Romeo" | Basement Jaxx |
| 23 June | "Booo!" | Sticky featuring Ms. Dynamite |
| 30 June | "Obsession" / "Tear Out Me Heart" | Future Cut |
| 7 July | "Up All Night" / "Take Control" | John B |
| 14 July | "Another Chance" | Roger Sanchez |
| 21 July | "Castles in the Sky" | Ian Van Dahl |
| 28 July | "Meet Her at the Love Parade" | Da Hool |
| 4 August | "Witness " | Roots Manuva |
| 11 August | "Babarabatiri" | Gypsymen |
| 18 August | "21 Seconds" | So Solid Crew |
| 25 August | "Superstylin'" | Groove Armada |
| 1 September | "Hide U" | Kosheen |
| 8 September | "21st Century" | Weekend Players |
| 15 September | "Body Rock" | Shimon & Andy C |
| 22 September | "It Began in Afrika" | Chemical Brothers |
| 29 September | "Papua New Guinea" | Future Sound Of London |
| 6 October | "Right On!" | Silicone Soul |
| 13 October | "Jus 1 Kiss" | Basement Jaxx |
| 20 October | "Flawless" | The Ones |
| 27 October | "Sambuca" | Wideboys featuring Dennis G |
| 3 November | "Sambuca" | Wideboys featuring Dennis G |
| 10 November | "Rapture" | iiO |
| 17 November | "They Don't Know" | So Solid Crew |
| 24 November | "They Don't Know" | So Solid Crew |
| 1 December | "Thunderball" / "Lazy Bones" | Moving Fusion |
| 8 December | "Gotta Get Thru This" | Daniel Bedingfield |
| 15 December | "Gotta Get Thru This" | Daniel Bedingfield |
| 22 December | "Gotta Get Thru This" | Daniel Bedingfield |
| 29 December | "Gotta Get Thru This" | Daniel Bedingfield |