List of UK Dance Singles Chart number ones of 2000
These are The Official UK Charts Company UK Dance Chart number one hits of 2000.
| Issue date | Song | Artist |
| 1 January | "A Little Bit of Luck" | DJ Luck & MC Neat |
| 8 January | "A Little Bit of Luck" | DJ Luck & MC Neat |
| 15 January | "A Little Bit of Luck" | DJ Luck & MC Neat |
| 22 January | "Rise" | Eddie Amador |
| 29 January | "Pitchin' " | Hi-Gate |
| 5 February | "Hear You Calling" | Aurora |
| 12 February | "Breathe and Stop" | Q-Tip |
| 19 February | "Must Be the Music" | Joey Negro featuring Taka Boom |
| 26 February | "I'm in Love" | Starparty |
| 4 March | "Movin' Too Fast" | Artful Dodger and Romina Johnson |
| 11 March | "Movin' Too Fast" | Artful Dodger and Romina Johnson |
| 18 March | "Stop Playing with My Mind" | Barbara Tucker |
| 25 March | "Stop Playing with My Mind" | Barbara Tucker |
| 1 April | "Right Before My Eyes" | N'n'G featuring Kallaghan |
| 8 April | "Right Before My Eyes" | N'n'G featuring Kallaghan |
| 15 April | "Flowers" | Sweet Female Attitude |
| 22 April | "Toca's Miracle" | Fragma |
| 29 April | "Imagine " | Shola Ama |
| 6 May | "Crazy Love" | MJ Cole |
| 13 May | "Heart of Asia" | Watergate |
| 20 May | "Tell Me Why " | Paul Van Dyk featuring Saint Etienne |
| 27 May | "Masterblaster 2000" | DJ Luck & MC Neat featuring JJ |
| 3 June | "It Feels So Good" | Sonique |
| 10 June | "On the Beach" | York |
| 17 June | "Girls Like Us" | B-15 Project featuring Crissy D and Lady G |
| 24 June | "Sandstorm" | Darude |
| 1 July | "The Power of Love" | Frankie Goes to Hollywood |
| 8 July | "Voices" | Bedrock |
| 15 July | "Beautiful" | Matt Darey featuring Marcella Woods |
| 22 July | "I Need Your Lovin " | Marc et Claude |
| 29 July | "Sing-A-Long" | Shanks & Bigfoot |
| 5 August | "Fly Bi" | Teebone featuring MC Kie & MC Sparks |
| 12 August | "Time to Burn" | Storm |
| 19 August | "I Feel for You" | Bob Sinclar |
| 26 August | "Groovejet " | Spiller featuring Sophie Ellis-Bextor |
| 2 September | "Groovejet " | Spiller featuring Sophie Ellis-Bextor |
| 9 September | "Freak Like Me" | Tru Faith & Dub Conspiracy |
| 16 September | "Lady " | Modjo |
| 23 September | "Scorchio" | Sasha/Emerson |
| 30 September | "Kernkraft 400" | Zombie Nation |
| 7 October | "Sorry " | Monsta Boy featuring Denzie |
| 14 October | "Silence" | Delerium featuring Sarah McLachlan |
| 21 October | "Dooms Night" | Azzido Da Bass |
| 28 October | "Pasilda" | Afro Medusa |
| 4 November | "Gettin' in the Way" | Jill Scott |
| 11 November | "Greed" / "The Man with the Red Face" | Laurent Garnier |
| 18 November | "138 Trek" | DJ Zinc |
| 25 November | "One More Time" | Daft Punk |
| 2 December | "Operation Blade " | Public Domain |
| 9 December | "Phatt Bass" | Warp Brothers vs. Aquagen |
| 16 December | "Dedicated to Love" | Marissa |
| 23 December | "Storm Animal" | Storm |
| 30 December | "Operation Blade " | Public Domain |