| Rank | Title | Studio | Actor | Director | Gross |
| 1. | ' | 20th Century Fox | Ewan McGregor, Natalie Portman, Hayden Christensen, Ian McDiarmid, Samuel L. Jackson, Christopher Lee, Anthony Daniels, Kenny Baker and Frank Oz | George Lucas | $380,270,577 |
| 2. | Harry Potter and the Goblet of Fire | Warner Bros. Pictures | Daniel Radcliffe, Rupert Grint, Emma Watson, Robbie Coltrane, Ralph Fiennes, Michael Gambon, Brendan Gleeson, Jason Isaacs, Gary Oldman, Alan Rickman, Maggie Smith and Timothy Spall | Mike Newell | $273,281,180 |
| 3. | War of the Worlds | Paramount Pictures | Tom Cruise, Dakota Fanning, Miranda Otto and Tim Robbins | Steven Spielberg | $234,280,354 |
| 4. | ' | Walt Disney Studios | William Moseley, Anna Popplewell, Skandar Keynes, Georgie Henley, Tilda Swinton, James McAvoy, Jim Broadbent and Liam Neeson | Andrew Adamson | $209,440,087 |
| 5. | Wedding Crashers | New Line Cinema | Owen Wilson, Vince Vaughn, Christopher Walken, Rachel McAdams, Isla Fisher and Jane Seymour | David Dobkin | $209,253,921 |
| 6. | Charlie and the Chocolate Factory | Warner Bros. Pictures | Johnny Depp, Freddie Highmore, David Kelly, Helena Bonham Carter, Noah Taylor, Missi Pyle, James Fox, Deep Roy and Christopher Lee | Tim Burton | $206,459,076 |
| 7. | Batman Begins | Warner Bros. Pictures | Christian Bale, Michael Caine, Liam Neeson, Katie Holmes, Gary Oldman, Cillian Murphy, Tom Wilkinson, Rutger Hauer, Ken Watanabe and Morgan Freeman | Christopher Nolan | $205,343,774 |
| 8. | Madagascar | DreamWorks Pictures | voices of Ben Stiller, Chris Rock, David Schwimmer and Jada Pinkett Smith | Eric Darnell and Tom McGrath | $193,595,521 |
| 9. | Mr. & Mrs. Smith | 20th Century Fox | Brad Pitt, Angelina Jolie, Adam Brody and Kerry Washington | Doug Liman | $186,336,279 |
| 10. | Hitch | Columbia Pictures | Will Smith, Eva Mendes, Kevin James, Amber Valletta, Michael Rapaport and Adam Arkin | Andy Tennant | $179,495,555 |
