On 26 April 1709, Marie Louise was married to John William Friso, Prince of Orange. He was the eldest surviving son of Henry Casimir II, Prince of Nassau-Dietz, and Henriëtte Amalia of Anhalt-Dessau; he had inherited his title in 1702 from the childless William III, Prince of Orange, due to his descent from both William the Silent and Frederick Henry, Prince of Orange. The events behind their betrothal began after John William was almost killed by cannon fire and roundshot on two occasions. His mother, Henriette Amalia, perhaps realizing how vulnerable her son was, quickly began looking for a suitable bride to ensure an heir. In the end, the choice came down to two German princesses. She apparently informed him that he should think of the choice as between two chairs, and that he should choose the most comfortable of the two. John duly traveled to Hesse-Kassel and became engaged to the 20-year-old Marie Louise within a week. He did not even bother meeting the other candidate. The main factor in this decision was probably that Marie Louise's father was a trusted general under the well-respected Duke of Marlborough. In addition, marriage to a daughter of the Landgrave of Hesse-Kassel would also have served to strengthen John William's place among the other ruling houses. Marie Louise was not considered attractive, as her features were heavy and her face was dominated by a large nose. She was however very charming, and greeted those of all ranks with natural friendliness and sincere concern for their well being. They had two children before his untimely death by drowning on 14 July 1711, the youngest of whom was born after his death. William Charles Henry Friso's birth was met with great relief by the Frisians, and he automatically inherited the title Prince of Orange.
First Regency
Since her husband died while she was pregnant, her son William immediately became Prince of Orange upon his birth six weeks later. Marie Louise served as regent for her son from 1711 until he reached his majority in 1731. This regency was granted despite her inexperience with the affairs of her adopted country. Although she did not have any experience, Marie Louise successfully withstood a series of natural disasters, which included a sequence of bad harvests and severe winters from 1712 to 1716. At the time of her marriage, Marie Louise quickly earned the affection of the Dutch population. She was known as a woman of intelligence and sensitivity, and was often fondly referred to as Marijke Meu. She also dealt with a major problem concerning shipworms – parasites that upon arriving on ships from the Far East, proceeded to devour wooden sections of the vital, protective dykes. These damages threatened to collapse the entire dyke system, which would have destroyed vast amounts of land used for farming in the Dutch province of Friesland. The money needed to prevent such an occurrence from happening was hard to raise however; tax obligations to the Hague from this province were seldom realistically reviewed. In order to end the looming starvation, Marie Louise traveled to the Hague and pleaded in person before the States-General for help. She apparently spoke so eloquently that she returned home with not only a remittance on taxation, but also with a sizable detachment of soldiers to help repair the dykes. After a 1736 visit, Marie Louise maintained a correspondence, in "abominable French," with religious and social reformer Count Nikolaus Ludwig of Zinzendorf and Pottendorf. A deeply religious woman, she provided sanctuary to persecuted Protestants fleeing the Catholic Habsburgs. Despite her son's objections, Marie Louise allowed a group of Moravians to settle in the barony of IJsselstein, of which she was baroness.
Traits and relationship with children
After her husband died, Marie Louise found herself a 23-year-old widow residing in a foreign country. She became inherently pessimistic and agonized over the affairs of her children. This pessimistic trait passed onto her daughter Amalia as well, causing her to be melancholy and withdrawn her whole life. Her son William inherited her heavy Germanic looks, rather than "the finely etched ascetic looks which his father had shared with William III". William was sickly as a child, and was rigidly disciplined and educated by Marie Louise with great care in the city ofLeeuwarden. Marie Louise had a good relationship with her son, so that by the time of his coming of age in 1729, she was invited to take equal part in the celebrations. In his youth, she sent him daily letters reminding him to do such things as brush his teeth and get plenty of sleep; he duly responded to each letter patiently. Marie Louise was described to be frugal, especially in comparison to the excesses of her mother-in-law Henriette Amalia. Due to this frugality, she was able to give large sums to various charitable causes. On one occasion, a nobleman offered her lavish hospitality; she replied by asking if he did not feel guilty at using money he could have donated to the poor.
Son's marriage
Marie Louise's son William married Anne, Princess Royal, eldest daughter of George II of Great Britain, on 25 March 1734 at St James's Palace in London. Upon return of thewedding party to the Netherlands, William had written his mother, warning her that Anne was allowed precedence over Marie Louise because she was his wife and a king's daughter. This warning was hardly needed, as Marie Louise had eagerly exited Prinsenhof as soon as her son came of age, opting to live in an elegant but unpretentious house in Harlingen. She had long displayed her disinterest in royal technicalities and the royal lifestyle. She welcomed her son and his new wife upon their arrival, but then returned to her quiet house, taking no part in their ceremonious entry.
