Zimmer's career began with stage work; an early television role was her portrayal of the character of Bonnie Harmon on One Life to Live in 1978. In 1979, she was tapped to replace Kathleen Turner as Nola Dancy Aldrich on The Doctors. She later appeared opposite Turner in the 1981 film Body Heat in a plot that addressed similarities in their appearance. For much of her stint, she was the show's leading lady, but left the show in July 1982 on a maternity leave, escorted off the show by her real life husband, A.C. Weary, who played Nola's newest conquest. She would return one last time later in the year for the funeral of her former mother-in-law, Mona Croft. She had a brief return to One Life to Live from February through November 1983 as Echo DiSavoy. In 1983, Zimmer was cast in the role for which she is best known, the character of Reva Shayne on the television soap opera Guiding Light. Her portrayal of Reva was a focus of the show until Zimmer left in 1990. She returned to Guiding Light in April 1995 and portrayed Reva until the show's conclusion in September 2009. While Zimmer's Reva was paired with several leading men, her work with Robert Newman earned them the label of "supercouple." Zimmer left Guiding Light in July 1990 and moved to the West Coast for five years, during which she played Jodie DeWitt Walker on Santa Barbara from 1992 to 1993. In 1995, Zimmer appeared in an episode of Seinfeld, as Mr. Pitt's attorney, who suspected Elaine and Jerry were trying to kill Mr. Pitt. In 2010, Zimmer returned to the role of Echo on One Life to Live. Zimmer was featured in a story along with former Guiding Light co-star Jerry verDorn', Robin Strasser' and Erika Slezak . Zimmer has also appeared in several episodic television programs, including Designing Women, MacGyver, Models, Inc., and Babylon 5. She also appeared in several made-for-television movies. Zimmer has starred in a number of theater roles, including several at Augusta's Barn Theatre. In 2011, it was announced that Zimmer would be cast in the Off-Broadway international hit Love, Loss, and What I Wore. She starred as Mrs. Hayes in Connecticut Repertory Theatre's production of Odysseus D.O.A., running through March 4, 2012. Zimmer made her musical theatre debut when she joined the first North American tour of Broadway's Wicked. She played the role of Madame Morrible from 14 August 2012 through 13 December 2013. Zimmer returned to the role with the first North American tour on 30 September 2014. Zimmer has also appeared in several productions of the musical Gypsy, first in 2006 at the Barn Theatre in Augusta, Michigan, and in 2015 at the Pittsburgh Civic Light Opera opposite former Guiding Light leading man Robert Newman. In 2011 she released her memoir called I'm Just Sayin'!: Three Deaths, Seven Husbands and a Clone! My Life as a Daytime Diva.
