Lombardi taught in the history department at Indiana University, first at the Jeffersonville, Indiana branch campus and then at the main campus in Bloomington, Indiana, from 1967 through 1987. At Indiana, he held various administrative posts, including director of Latin American studies, dean of international programs, and dean of arts and sciences. He served as the provost and vice president for academic affairs at Johns Hopkins University in Baltimore, Maryland from 1987 through 1990. As the provost of Johns Hopkins, Lombardi played a key role in fund-raising and in resolving a financial crisis in which the university was then embroiled. Lombardi is a specialist in Latin American history, and has a particular interest in Venezuela. He has written numerous academic journal articles and several books on Venezuela and Latin American history and affairs, as well as on many university administration-related subjects. He is a nationally recognized authority on American higher education, and has been the co-editor of the annual editions of The Top American Research Universities from 2000 to the present. In addition to Latin American history classes, he has taught courses on intercollegiate sports, international business and university management.
University of Florida
Lombardi served as the ninth president of the University of Florida located in Gainesville, Florida, from 1990 to 1999. He was barely settled in his job at the beginning of the fall 1990 semester when Lombardi was confronted by one of the most serious crises in the university's history—the horrific murders of five students by serial killerDanny Rolling. He is remembered as both comforter-in-chief and as a "student's president" during his term as president. As part of his athletics reform agenda, Lombardi created the Committee on Intercollegiate Athletics, which ultimately removed responsibility for student-athlete academics from the control of the University Athletic Association and placed it under the control of the committee. Lombardi actively reinserted the office of the president in the UAA's chain of decision-making; the president retained final authority over all major decisions. He implemented further institutional controls intended to promote the welfare and academic achievement of student-athletes and continued compliance with the rules of the National Collegiate Athletics Association. Lombardi was also responsible for the selection of Jeremy Foley as the new athletic director in 1992, now recognized as one of the most successful athletic directors in NCAA Division I sports. His relationships with the Florida Board of Regents and the Florida Legislature were characterized by a series of ups and downs, confrontation followed by conciliation, usually involving conflicts over declining state financial support and conflicting state education funding priorities of the legislature. Lombardi resigned as president in 1999, but continued to teach as a member of the history faculty until 2002. Lombardi's enthusiasm for classic cars led him and a friend to operate Farmer's Garage, a specialty shop for older model automobiles. At the University of Florida, he is fondly remembered for driving about the Gainesville campus in an old red pickup truck.
As president of the LSU System, Lombardi served as the chief executive officer of the five campuses, eleven institutions and ten hospitals within the system. He presided over the groundbreaking of the University Medical Center in New Orleans. He also held an appointment as a history professor at Louisiana State University. He was terminated from the position on Friday, April 27, 2012.