John Spence

• John Brodie Spence
• John C. H. Spence
• John David Spence
• John P. Spence (politician)
• John S. Spence
• John Selby Spence (bishop)
• John Spence (footballer)
• John Spence (frogman)
• John Spence (musician)
• John Spence (politician)
• John Spence (sailor)
• John Spence (scientist)
• John Spence (zoo director)
• John Spence Community High School
• John Spencer (disambiguation)
• Johnnie Spence
• Jonathan Spence