James O'Brien

• George C. Parker
• James Bronterre O'Brien
• James C. O'Brien
• James F. O'Brien
• James Francis Xavier O'Brien
• James H. O'Brien
• James Joseph O'Brien
• James O'Brien (1695–1771)
• James O'Brien (1806–1882)
• James O'Brien (Canadian politician)
• James O'Brien (New Brunswick politician)
• James O'Brien (New Zealand politician)
• James O'Brien (U.S. Congressman)
• James O'Brien (athlete)
• James O'Brien (broadcaster)
• James O'Brien (filmmaker)
• James O'Brien (horticulturist)
• James O'Brien (hurler)
• James O'Brien (internet radio)
• James O'Brien (oceanographer)
• James O'Brien (piper)
• James O'Brien, 3rd Marquess of Thomond
• Jamie O'Brien (disambiguation)
• Jay O'Brien (Virginia politician)
• Jim O'Brien (disambiguation)
• Special Envoy for Hostage Affairs
• The Boat People (band)
• Victoria Medal of Honour