Thompson was born in Paramount, California and grew up in Downey, California. He originally attended La Serna High School where he was named honorable mention All-San Gabriel Valley League as a sophomore as the Lancers went on to win the 2013 CIF Southern Section title. He transferred to Downey High School following his sophomore year where he played both wide receiver and cornerback and was named All-CIF and All-San Gabriel Valley League in his junior and senior seasons. As a senior, Thompson intercepted five passed and averaged 20.2 yards per reception and was named to the All-Area Dream Team by the Long Beach Press-Telegram. Thompson was rated a three-star recruit by ESPN, Rivals and Scout and the No. 56 cornerback nationally by ESPN.com. He ultimately committed to play college football at Washington State over offers from San Diego State, New Mexico State, Army, and Navy.
College career
Thompson entered Washington State as an early enrollee and participated in the Cougars' spring practices. He was named the starting strong safety entering the season and was named a True Freshman All-American by ESPN after recording 51 tackles and a team-leading seven pass breakups in 13 games. As a sophomore, Thompson led the Cougars with 73 tackles, including 5.5 for loss, two pass breakups and four interceptions and lead the conference with three fumble recoveries and was named second team All-Pac-12 Conference and first team all-conference by the Associated Press. Thompson entered his junior season on the Chuck Bednarik Award watchlist and recorded 67 tackles along with two interceptions and eight passes broken up and was named honorable mention all-conference. Thompson lost his final season of eligibility due to a violation of NCAA rules going into his senior season, which was reportedly due to purchasing a non-steroid over-the-counter supplement that is banned by the NCAA. Over the course of his collegiate career, Thompson started all 39 of Washington State's games while on the team and finished with 191 tackles with six interceptions and 17 passes broken up.
Professional career
After being declared ineligible for his final season at Washington State, Thompson entered the 2019 NFL Supplemental Draft. He was selected by the Arizona Cardinals in the fifth round of the supplemental draft and was the only player selected. He signed a four-year contract with the Cardinals on July 17, 2019. Thompson made his NFL debut on September 8, 2019 against the Detroit Lions, playing seven snaps on special teams. He made his first career start on October 6, 2019 against the Cincinnati Bengals, making eight tackles in a 26-23 win. Thompson recorded his first career interception on November 17, 2019, picking off a pass from San Francisco 49ers quarterback Jimmy Garoppolo in the fourth quarter of a 36-26 loss. He finished his rookie season with 57 tackles, three passes defended and an interception in 15 games played, starting nine of the Cardinals final 12 games.
