Issac
Issac may refer to:Given name
- Issac Blakeney, American football wide receiver
- Issac Booth, American football player
- Issac Ryan Brown, American child actor and singer
- Issac Delgado, Cuban-Spanish musician, and salsa performer
- Issac Honey, Ghanaian footballer
- Issac Koga, Japanese electronics researcher/engineer
- Issac Luke, New Zealand rugby league hooker
- Issac Osae, Ghanaian footballer
Surname
- Osthatheos Issac, Syriac Orthodox bishop
- Rod Issac, American football cornerback
Places
- Issac, Dordogne, a commune in France.