Isodisomy


Isodisomy is a non-mendelian trait in humans caused by both copies of a chromosome pair being inherited from the biological mother or the father. It differs from uniparental disomy in that instead of receiving an identical pair of chromosomes from one parent, the fertilized ovum contains a complete pair of chromosomes from one parent resulting in a complete pair of chromosomes from only one parent. This may result in the expression of recessive traits in the offspring. Some authors use the term uniparental disomy and isodisomy interchangeably.
This genetic abnormality can result in the birth of a normal child who has no obvious disability. It is associated with abnormalities in the growth of the offspring and in the placenta.