Intercalated cells of the amygdala
The intercalated cells of the amygdala are a group of GABAergic neurons situated between the basolateral and central nuclei of the amygdala that are important for inhibitory control over the amygdala.Function
ITC cells are thought to play a role as the 'off switch' for the amygdala, inhibiting the amygdala's central nucleus output neurons and its basolateral nucleus neurons. Some researchers speculate that ITC cells, via their extensive local inhibition within the amygdala, could serve as a substrate for expression and storage of extinction memory.Structure
Connectivity
ITC cells receive strong projections from the infralimbic cortex in both primates and rodents, which may explain cortical control over emotional regulation processes such as extinction.
