After starting at Apple as an intern in 1995, Chaudhri spent 19 years with the Human Interface team, later becoming the team's director of design. He and fellow designer Bas Ording met at Apple in the late-1990s, and soon after Chaudhri joined Ording on the User Interface team. As leaders of Apple's UI team, they updated the appearance of the Mac operating system, including pulsating buttons, animated progress bars, and a glossy, transparent look. They worked for years on building a new interface based entirely on touch and features like replacing zoom buttons with pinch to zoom, and being able to scroll by flicking the screen. Chaudhri is named as an inventor on Apple's touch screen patent, which covers functional aspects of multitouch screens such as the iPhone and iPad. Chaudhri was one of six members of the original iPhone design team, who created the interface of the first iPhone. He previously led the design for Dashboard on the Mac, a widget interface that some parts migrated to iPhone. Chaudhri developed a grid of square app icons to organize the iPhone's functions, known as SpringBoard. The iPhone's rectilinear app icon design also came from Chaudhri. He is also the inventor of the jiggling effect during user interface reconfiguration mode, worked with designer Freddy Anzures on the iPhone's slide to unlock feature, designed the iPhone's Do Not Disturb feature, and helped convince Steve Jobs that the iPhone should simply have one button. His patent for a graphical user interface for a display screen, which covers the icon layout that appears on the iPhone, was one of three patents that were the centerpiece of a lawsuit between Apple and Samsung to determine how much Samsung should pay Apple for infringing on three of its design patentscovering early versions of the iPhone. In 2016, Samsung was ordered to pay $399 million in damages. Chaudhri is a named inventor alongside Steve Jobs on Apple's iPod patent. Many of his patents were featured as part of a 2012 exhibition at the Smithsonian Institution, The Patents and Trademarks of Steve Jobs: Technology that Changed the World. Chaudhri left Apple in early 2017 to form his own technology company, Humane, along with his wife, Bethany Bongiorno, who he met while both were working on the iPad. The company uses artificial intelligence, machine learning, and computer vision technology to enhance the human-device relationship.