Iacopo

• Iacopo II Appiani, the lord of Piombino from 1405 until 1441
• Iacopo III Appiani, Prince of Piombino of the Appiani dynasty in the Renaissance
• Iacopo IV Appiani, Italian condottiero and lord of Piombino of the Appiani dynasty in the Renaissance
• Iacopo V Appiani, the lord of Piombino of the Appiani dynasty from 1511 until his death
• Iacopo Balestri, Italian footballer
• Iacopo Jacomelli, Italian singer of 1940s
• Iacopo La Rocca, Italian football defender
• Iacopo Rusticucci, 13th century Florentine politician
• Vitaliano di Iacopo Vitaliani, Paduan nobleman who lived in the late 13th century around the time of Giotto and Dante