IL3RA
Interleukin 3 receptor, alpha , also known as CD123, is a human gene.Function
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3, colony stimulating factor 2, and interleukin 5. The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y.Interactions
IL3RA has been shown to interact with Interleukin 3.
