Hydroxyflutamide


Hydroxyflutamide , or 2-hydroxyflutamide, is a nonsteroidal antiandrogen and the major active metabolite of flutamide, which is considered to be a prodrug of hydroxyflutamide as the active form. It has been reported to possess an IC50 of 700 nM for the androgen receptor, which is about 4-fold less than that of bicalutamide.