Human parechovirus 1 (HPeV1) cis regulatory element (CRE)


The Human Parechovirus 1 cis regulatory element is an RNA element which is located in the 5'-terminal 112 nucleotides of the genome of human parechovirus 1. The element consists of two stem-loop structures together with a pseudoknot. Disruption of any of these elements impairs both viral replication and growth.