Holin superfamily V
The Holin superfamily V is a superfamily of integral membrane transport proteins. It is one of the seven different holin superfamilies in total. In general, these proteins are thought to play a role in regulated cell death, although functionality varies between families and individual members. The Holin superfamily V includes the TC families:
Superfamily V includes protein families classified in the Transporter Classification Database as and . Both families possess members from Firmicutes, Actinobacteria and Chloroflexi. Proteins of this superfamily all appear to have 3 transmembrane segments and have average sizes of 97 and 101 amino acyl residues, respectively.
