Hesperidin


Hesperidin is a flavanone glycoside found in citrus fruits. Its aglycone form is called hesperetin. Its name is derived from the word "hesperidium", for fruit produced by citrus trees.
Hesperidin was first isolated in 1828 by French chemist Lebreton from the white inner layer of citrus peels.
Hesperidin is believed to play a role in plant defense.

''Rutaceae''

contains hesperidin.
280 nm chromatogram after UHPLC separation of commercial orange juice. Hesperidin is peak at 16.44 min.

Content in foods

Approximate hesperidin content per 100 ml
, an enzyme that uses hesperidin and H2O to produce hesperetin and rutinose, is found in the Ascomycetes species.

Research

As a flavanone found in the rinds of citrus fruits, hesperidin is under preliminary research for its possible biological properties in vivo. One review did not find evidence that hesperidin affected blood lipid levels or hypertension. Another review found that hesperidin may improve endothelial function in humans, but the overall results were inconclusive.