Hedgehog Signaling Pathway
Hedgehog Signaling Pathway - In the absence of the Hh ligand, the receptor PTCH (Patched) acts to prevent high expression and activity of SMO (Smoothened). When Hh is bound, the repression of SMO is relieved which leads to activation of the GLI transcription factors: activat.... Main subjects: signaling pathway, signaling pathway pertinent to development.
