Haplogroup O-M117


Haplogroup O2a2b1a1-M117 is a subclade of O2a2b1-M134 that occurs frequently in China and in neighboring countries like Nepal, Bhutan, and Korea, especially among Sino-Tibetan language speaking people.
O2-M117 has been detected in samples of Tamang, Tibetans, Tharus, Han Taiwanese, Newars, the general population of Kathmandu, Nepal, Han Chinese, Tungusic peoples from the PRC, and Uyghurs .
Like O-M7, O-M117 has been found with greatly varying frequency in many samples of Hmong-Mien-speaking peoples, such as Mienic peoples, She, and Hmongic peoples .
In Meghalaya, a predominantly tribal state of Northeast India, O-M133 has been found in 19.7% of a sample of the Tibeto-Burman-speaking Garos, but in only 6.2% of a pool of eight samples of the neighboring Khasian-speaking tribes.

Origin

The earliest attested genealogical split within haplogroup O-M117, that between O-M133 and O-M117, is estimated to have occurred approximately 11,900 ybp. However, members of O-M117 are quite rare among extant humans. O-M117 has been observed in 2.2% of the CHB sample of the 1000 Genomes Project. In commercial testing, O-MF1380 or O-CTS4960, which belongs to O-M117, has been found in one individual who has reported an origin in Guangdong, one individual who has reported an origin in Jiangsu, one individual who has reported an origin in Chongqing, one individual who has reported an origin in Indonesia, and one individual who has reported an origin in Japan. O-M117 also has been found in 1.5% of a sample collected in Daejeon, South Korea and in 1.0% of a sample collected in Seoul, South Korea.
The most recent common ancestor of all extant members of the O-M133 subclade, which predominates among extant members of O-M117, is estimated to have lived in a significantly less ancient era: 7,200 ybp according to YFull, 7,455 years ago according to Karmin et al. 2015, or 7,500
or 6,400 years ago according to Poznik et al. 2016.

Distribution

China

Haplogroup O-M117 or O-M133 has been found often in samples of Han Chinese from various parts of China: 10/34 = 29.4% O-M133 Hakka in Taiwan, 57/258 = 22.1% O-M133 miscellaneous Han volunteers in Taiwan, 4/19 = 21.1% Fujian, 12/60 = 20.0% O-M133 Minnan in Taiwan, 29/167 = 17.4% East China, 21/129 = 16.3% North China, 7/46 = 15.2% Beijing, 5/34 = 14.7% Chengdu, 5/35 = 14.3% Harbin, 9/65 = 13.8% South China, 7/55 = 12.7% O-M133 Fujian, 4/35 = 11.4% Meixian, 3/30 = 10.0% Lanzhou, 2/32 = 6.3% Yili, 1/37 = 2.7% Hunan.
Members of haplogroup O-M117 also have been found among various ethnic minorities in China, such as Tibetans, Dai, She people, Koreans, Hezhe, Evenks, Manchu, Yao in Liannan, Guangdong, Mongols, Qiang, Daurs, Hani, Xibe, Uyghurs, Oroqen, Buyi, and Hui.

India

In a study of the DNA of Adivasi populations in the state of Meghalaya, Reddy et al. found O-M133 in 19.7% Garo, 13.6% Pnar, 11.1% Nongtrai, 8.3% Lyngngam, 6.9% War-Khasi, 6.3% Maram, 5.3% War-Jaintia, 2.3% Khynriam, and 0% Bhoi. The Garo natively speak the Garo language, whereas all the other studied populations natively speak Khasic languages.
In another study that included populations in Meghalaya, Kumar et al. found O-M133 in 9.8% Khasi and 9.1% Garo.
A study of populations of northern West Bengal and Sikkim published in 2011 found O-M117 in 57.7% Rabha, 47.4% Mech, 43.1% Rajbanshi, 41.7% Dhimal, and 7.4% Bengali from the northern panhandle of West Bengal and in 9.1% of a sample of Lachungpa from Sikkim. O-M117 was not found in this study's samples of Kol, Santhal, Kharia, or Oraon from the northern panhandle of West Bengal.

Japan

A study published in the year 2000 found O-M117 in 4.3% of a sample representing Japan. In a study published by Chinese researchers in the year 2006, O-M117 was found with high frequency in a sample of Japanese of undescribed geographical origin. However, in a study published by Japanese researchers in the year 2007, the same haplogroup was found with much lower frequency in a larger sample of Japanese from various regions of Japan. O-M117 has been found in 8.8% of the JPT sample of the 1000 Genomes Project.

Korea

Between 11% and 15% of males in samples collected in South Korea have been found to belong to haplogroup O-M117 or O-M133.

Mongolia

Haplogroup O-M117 has been found in about 5% of samples of Mongols in Mongolia: 4/20 = 20.0% NE Mongolia, 1/18 = 5.6% central Mongolia, 3/65 = 4.6% Outer Mongolian, 1/23 = 4.3% SE Mongolia, 3/97 = 3.1% NW Mongolia.

Nepal

Haplogroup O-M117 has been found in 84.4% of a sample of Tamang, 33.3% of sample of Tharu of Chitwan and Morang, 21.2% of a sample of Newar, and 16.9% of a sample of the general population of Kathmandu.

Laos

In a study published in 2011, haplogroup O-M117 has been found in 7.8% of a sample of Hmong Daw in Laos and in 5.1% of a set of ethnic minorities who speak various Austroasiatic languages: 32.1% Bit, 16.2% Kataang, 14.0% Mal, 13.7% Khmu, 6.9% Xinhmul, 3.3% Alak, 2.94% Inh, 2.86% Talieng, 2.0% Laven, 2.0% Oy, 2.0% So, 0% Bo, 0% Brau, 0% Jeh, 0% Lamet, 0% Ngeq, 0% Aheu, 0% Suy, and 0% Katu.
Kutanan et al. 2019 found O-F8/F42, which is currently considered to be phylogenetically equivalent to O-M133, in 25.0% of a sample of Laotians from Luang Prabang and 5.0% of a sample of Laotians from Vientiane.

Thailand

In a study published in 2014, haplogroup O-M133 has been found in 13.3% of a sample of the general population of Thailand and in 3.7% of a sample of Akka in Thailand.
Brunelli et al. have found O-M117 in 35.0% of Shan, 22.4% of Khon Mueang, 22.2% of Mon, 20.0% of Western Lawa, 17.6% of Tai Lue, 16.7% of Tai Khuen, 13.6% of Tai Yuan, and 11.5% of Tai Yong in Northern Thailand and in 31.6% of Tai Yuan in Central Thailand. However, in the same study, haplogroup O-M117 was not observed in a sample of 25 Eastern Lawa in Northern Thailand.
Kutanan et al. have found O-F8/F42 in 14.75% of a pool of samples from Thailand, including 50.0% Palaung in Northern Thailand, 38.9% Shan in Northern Thailand, 33.3% Khon Mueang in Northern Thailand, 31.0% Karen in Northern Thailand, 28.6% Nyahkur in Northeast Thailand, 23.5% Kaleun, 17.1% Thai, 16.7% Tai Lue in Northern Thailand, 16.7% Nyaw in Northeast Thailand, 16.7% Blang in Northern Thailand, 15.4% Tai Yuan, 14.3% Mon, 14.3% Phuan, 11.8% Soa, 11.8% Tai Khün, 9.4% Western Lawa, 8.3% Black Tai, 6.5% Lao Isan, and 5.6% Khmu.

Vietnam

Haplogroup O-M133 has been found in 4/46 = 8.7% of the KHV sample of the 1000 Genomes Project. Haplogroup O-M133 has been found in 1/24 = 4.17% of a sample of people in Hanoi, Vietnam. A study published in 2011 found haplogroup O-M117 in 1/15 = 6.67% Kinh and 1/12 = 8.33% Muong.

Subclades

According to the ISOGG experiental tree， the subclades of O2ab1a1-M117 had shown as below :
  • O2a2b1a1
  • *O2a2b1a1a
  • **O2a2b1a1a1
  • ***O2a2b1a1a1a
  • ****O2a2b1a1a1a1
  • ****O2a2b1a1a1a2
  • *****O2a2b1a1a1a2a
  • ****O2a2b1a1a1a3
  • ****O2a2b1a1a2
  • *****O2a2b1a1a2a
  • ******O2a2b1a1a2a1
  • *******O2a2b1a1a2a1a
  • **O2a2b1a1a3
  • ***O2a2b1a1a3a
  • ****O2a2b1a1a3a1
  • ***O2a2b1a1a3b
  • **O2a2b1a1a4
  • ***O2a2b1a1a4a
  • ****O2a2b1a1a4a1
  • **O2a2b1a1a5
  • ***O2a2b1a1a5a
  • ****O2a2b1a1a5a1
  • ***O2a2b1a1a5b
  • **O2a2b1a1a6
  • ***O2a2b1a1a6a
  • ***O2a2b1a1a6b
  • ****O2a2b1a1a6b1
  • *****O2a2b1a1a6b1a
  • *****O2a2b1a1a6b1b
  • ****O2a2b1a1a6b2
  • ****O2a2b1a1a6b3
  • *O2a2b1a1b

    Citations