The station used to have four lines running through between two platforms. The western platform is the original one. The other platform with ticket office is a replacement. It was built approximately where the southbound through line ran and then replaced the original. There was a turntable just to the south of the station on the east. The semi-circular retaining wall can still be seen. There was a signal box opposite at John Street level accessed from John Street. The goods yard was to the north of the station, encompassing the whole of the current bus station and car park. The goods yard entrance and main Station entrance was from adjacent to the top cross. There was a large retaining wall that ran from the cross up Quarry Street to about where the Quarry street steps now sit. The entry road ran adjacent to the wall and curved away from the wall as it approached the station and yard entrances. The Quarry street steps replaced an office, at street level, and set of steps leading down to the main Station platform. There is also an entrance to the other platform on the south side of the bridge. It has a grand arched stone portico but is sealed now with an ornate design facing the pavement. The steps are still existing but the archway to the platform is walled up. In addition there was a line that went from the position of the disused pedestrian bridge opposite South Park Road (site of another signal box. The line then went across Kemp Street and along the line of car parking in Graham Street then crossed Quarry Street to enter the gas works. This line terminate just before Selkirk Street. the line went through still extant gates beside the main line at Kemp Street. The entry gates to the gas works are also still existing. The line terminated just to the south of the larger gas tank that now only exists as a circular concrete pad. The working part of the gasworks with a vertical bucket line emerging above its roof was more or less where the print works is on Portland Place The platforms were connected by a covered overbridge. There were stairs on the north and ramps to the south. The "shadow" of the ramps can be seen on the Glasgow bound platform wall. There was an overall roof. Wooden cladding extended from the supporting walls to the edge of the platforms with only the girders passing across. There was a pair of lifts adjacent to the metal overbridge at the south end of the platforms. The overbridge still matches the original four lines. The line through the station was electrified in 1974, as part of the wider project to wire the northern end of the West Coast Main Line. In last 2016, construction began on a new, covered, passenger footbridge between the platforms. The new bridge will be compliant with disability regulations and feature lifts from the platforms to the bridge itself. In order to accommodate this the booking office on platform 2 and the waiting shelter on platform 1 have both been demolished, with tickets currently being sold from a temporary cabin next to the platform 2 entrance. Once the new bridge is completed in 2017, the existing footbridge will be removed and new passenger facilities constructed.
Services
2006/07
Since the re-opening of the Larkhall branch in December 2005, Hamilton Central has been served by four trains per hour towards . Two of these services run from to with a limited stopping pattern until Glasgow, with the other two from the Motherwell direction. In the south east direction, there are two trains per hour to / and two trains per hour to Larkhall.
2016
Following a major recast of the Argyle Line timetable in the wake of the electrification of the Whifflet Line, the service pattern from this station has altered significantly. There are still two trains per hour each to Motherwell and Larkhall, but one of the former now runs to Cumbernauld via Whifflet rather than Lanark. Glasgow-bound services meanwhile now call at all stations to Central Low Level and then proceed to Dalmuir via Clydebank or to. On Sundays, there is a train every half-hour each way to Motherwell and Milngavie and an hourly service each way on the Larkhall to Balloch route.
