Guatemala at the 2010 Summer Youth Olympics
participated in the 2010 Summer Youth Olympics in Singapore.
The Guatemalan squad consisted of 12 athletes competing in 8 sports: aquatics, equestrian, gymnastics, judo, modern pentathlon, sailing, shooting and weightlifting.
Medalists
| Medal | Name | Sport | Event | Date |
| Shooting | 10m Air Pistol Women Junior | 23 Aug |
Equestrian
Gymnastics
Artistic Gymnastics
;Girls| Athlete | Event | Score | Rank |
| Ana Sofía Gómez | Girls' Beam | 14.100 | 4 |
| Ana Sofía Gómez | Girls' Floor | 13.700 | 4 |
Judo
;Individual| Athlete | Event | Round 1 | Round 2 | Round 3 | Semifinals | Final | Rank |
| Athlete | Event | Opposition Result | Opposition Result | Opposition Result | Opposition Result | Opposition Result | Rank |
| Melva Marina Tobar Calderon | Girls' -78 kg | BYE | L 000-010 | Repechage W 101-000 | Bronze Medal Match L 000-010 | 5 |
Modern pentathlon
Sailing
;One Person Dinghy;Windsurfing
Shooting
;Pistol;Rifle
Swimming
Weightlifting
| Athlete | Event | Snatch | Clean & Jerk | Total | Rank |
| Nelson Anthony Mansilla Felipe | Boys' +85kg | 105 | 118 | 223 | 7 |