After clerking for a California superior court judge, Palmer decided to pursue real estate development of multifamily housing instead of law as a profession, founding GH Palmer Associates in 1978. Palmer opened his first major development in Santa Clarita, California in 1985. During the 1990s, Palmer focused on building more than 2000 market-rate housing in downtown Los Angeles and its suburbs. In 2001, Palmer completed the 632-unit Medici, the first of a series of downtown Italian-inspired apartment blocks situated beside freeways, which coincided with a revival of downtown Los Angeles. Other buildings in the "Renaissance Collection" built by Palmer include the Orsini, Visconti, Piero, Da Vinci, and Lorenzo. In 2006, Palmer applied for the Piero II, a mixed-use project, and requested that the City waive the affordable housing requirements. The City denied the waiver and Palmer sued the City of Los Angeles claiming the City's affordable housing zoning requirements in the Central City West specific plan violated the Costa-Hawkins Act. In 2009, the California Court of Appeal ruled that "as applied to Palmer's proposed project, the affordable housing ordinance conflicts with and is preempted by the vacancy decontrol provisions of the Costa-Hawkins Rental Housing Act." The City of Los Angeles later sued Palmer for negligence after another development, the Da Vinci, intentionally set fire by an arsonist currently in jail, damaged the adjacent freeway and a nearby city government building, eventually settling the case for $400,000. Palmer's most recent building, Broadway Palace Apartments, was completed in early 2017. Broadway Palace Apartments is designed in the Beaux-Arts style with a plaster and cast concrete ground level and top story, separated from the terracotta brick middle stories by string courses, moldings and changes in materials. Notable features include arched openings along the top story, dentils, brackets, pilasters and capitals. The facade fenestration and articulation resembles the historic 1920s-era buildings located on Broadway but different enough to appear new. Palmer has clashed with local government officials and activists, in part due to criticism of the style of his apartment buildings. Councilman Ed Reyes also criticized Palmer for the accidental destruction of an 1887 Victorian-style building. In 2015, Eddie Kim of the Los Angeles Downtown News described Palmer as both the "most prolific" and "most controversial" developer in downtown Los Angeles. Palmer, a strong opponent of mandatory affordable housing requirements for real estate development, appears in the Paradise Papers in connection with a Bermuda offshore to hold the registration for his private jet, which is done for security and maintenance reasons, yet he still pays the required California assesses property taxes on aircraft, which Bermuda does not. Palmer is worth an estimated US$3 billion.