In June 2003, Reisman served as an aquanaut during the mission aboard the Aquarius underwater laboratory, living and working under water for fourteen days.
Expedition 16/17
Reisman was assigned as a long duration crewmember on the International Space Station. He launched as Mission Specialist 5 aboard the STS-123 mission on March 11, 2008. After docking he took part in the first spacewalk of the mission. Reisman stayed on board as Flight Engineer 2 for part of Expedition 16 and part of Expedition 17. Having completed his mission, he returned to Earth as Mission Specialist 5 aboard STS-124 on June 14, 2008. During his time on board the ISS he had seen two visiting Space Shuttles and the installation of the Special Purpose Dexterous Manipulator and the pressurized section of the Japanese Experiment Module "Kibo". Reisman was the first Jewish crew member on the International Space Station. He sent a greeting from space to the people of Israel during the celebration of Israel's 60th Independence Day in May 2008. He also did an entertaining, high definition video of "A day in the life of a space station crew member" while on board as well as demonstrating in the large, and at the time empty, Kibo section, that humans cannot "swim" in the microgravity of orbital space.
STS-132
Reisman was a member of the STS-132 mission that traveled to the International Space Station aboard Space Shuttle Atlantis from May 14 to 26, 2010. He participated in two spacewalks during this mission.
Post-NASA career
On March 4, 2011, SpaceX announced that Reisman would be joining the company as a senior engineer working on astronaut safety and mission assurance. He was later promoted to director of crew operations. On May 31, 2018, Reisman announced he would leave his position at SpaceX, but remain as a "consultant," stating he could not pass up a job to teach human spaceflight at the nearby University of Southern California.
In popular culture
A self-proclaimed member of the "Colbert Universe", Reisman was interviewed live from space on the May 8, 2008 episode of The Colbert Report after being seen wearing a "WristStrong" bracelet. On July 24, 2008, after returning to Earth, Reisman appeared in person on The Colbert Report as that night's featured guest. Reisman presented Stephen Colbert with the WristStrong bracelet he had worn while in space. Reisman appeared on the final episode of The Colbert Report Reisman filmed a cameo appearance as a Colonial Marine for the series finale episode of Battlestar Galactica. Space.com reported that his scene, in which "someone throws up on him and then he dies", might not be in the final edit of the episode which aired March 20, 2009. In the podcast for the final episode, producer Ron Moore confirmed that one of the people seen in the background of a scene where a Raptor arms its nuclear payload was Reisman. Reisman served as technical advisor for the 2019 alternate historyApple TV+ show For All Mankind, also produced by Ron Moore. Reisman appeared on The Joe Rogan Experience on February 7, 2020. Reisman was a childhood classmate of actress Jane Krakowski. In May, 2010, Krakowski said on The Tonight Show with Jay Leno that she and Reisman exchanged e-mails while he was in space on Space Shuttle Atlantis. At the request of the crew, many of whom were 30 Rock fans, Krakowski provided an autographed script of the show which was brought into space.