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GL-II-73
GL-II-73
is a
benzodiazepine
derivative
related in
chemical structure
to
compounds
such as
midazolam
,
adinazolam
and the
active metabolite
of
rilmazafone
. It is described as an α
5
preferring
positive allosteric modulator
of the
benzodiazepine site
of
GABA
A
receptors
, with
weaker
activity
at α
2
and α
3
and no significant
affinity
for the α
1
subtype. In
animal tests
it was found to
produce
effects
consistent
with
antidepressant
,
anxiolytic
and
nootropic
actions
.
